The role of carotid plaque echogenicity in baroreflex sensitivity

Tsekouras, Nikolaos; Katsargyris, Αthanasios; Skrapari, Ioanna; Bastounis, Effie; Georgopoulos, Sotirios; Klonaris, Chris; Bakoyiannis, Christos; Bastounis, Elias

doi:10.1016/j.jvs.2010.11.121

Cited by 11 publications

(21 citation statements)

References 40 publications

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“…8,10,12,17,24,26,33 Echogenic atherosclerotic plaques are associated with reduced CSB sensitivity in comparison to echolucent ones. 59 Moreover, heavily calcified plaques not only require higher pressures for dilation, but they also more efficiently transmit these pressures to the carotid wall and to the CSBs. 8,18 Recent studies have suggested that patients with a small total plaque volume measured on computed tomography and fibrous tissue accounting for .60% of plaque volume on intravascular ultrasound virtual histology are more likely to develop HI.…”

Section: Discussionmentioning

confidence: 99%

Carotid Artery Stenting–Induced Hemodynamic Instability

Mylonas

Moulakakis

Antonopoulos

et al. 2013

Journal of Endovascular Therapy

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Section: Discussionmentioning

confidence: 99%

Carotid Artery Stenting–Induced Hemodynamic Instability

Mylonas

Moulakakis

Antonopoulos

et al. 2013

Journal of Endovascular Therapy

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“…Baroreflex sensitivity was found to be impaired in patients with bilateral carotid atherosclerosis (Nasr et al, 2005) or with echogenic plaques (Tsekouras et al, 2011). …”

Section: Introductionmentioning

confidence: 99%

Association between Carotid Intima Media Thickness and Heart Rate Variability in Adults at Increased Cardiovascular Risk

et al. 2017

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Background: Atherosclerotic carotid intima-media thickness (IMT) may be associated with alterations in the sensitivity of carotid baroreceptors. The aim of this study was to investigate the association between carotid IMT and the autonomic modulation of heart rate variability (HRV).Methods: A total of 101 subjects were enrolled in this prospective observational study. The carotid IMT was determined by duplex ultrasonography. The cardiac autonomic function was determined through HRV measures during the Deep Breathing Test. Linear regression models, adjusted for demographics, comorbidities, body mass index, waist-hip-ratio, and left ventricular ejection fraction were used to evaluate the association between HRV parameters and carotid IMT.Results: Participants had a mean age of 60.4 ± 13.4 years and an estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk score (using the Pooled Cohort Equations) of 16.4 ± 17. The mean carotid media thickness was highest (0.90 ± 0.19 mm) in the first quartile of the standard deviation of all RR intervals (SDNN) (19.7 ± 5.1 ms) and progressively declined in each subsequent quartile to 0.82 ± 0.21 mm, 0.81 ± 0.16 mm, and 0.68 ± 0.19 in quartiles 2 (36.5 ± 5.9 ms), 3 (57.7 ± 6.2 ms) and 4 (100.9 ± 22.2 ms), respectively. In multivariable adjusted models, there was a statistical significant association between SDNN and carotid IMT (OR −0.002; 95%CI −0.003 to −0.001, p = 0.005). The same significant association was found between carotid IMT and other measures of HRV, including coefficient of variation of RR intervals (CV) and dispersion of points along the line of identity (SD2).Conclusions: In a cohort of individuals at increased cardiovascular risk, carotid IMT as a marker of subclinical atherosclerosis was associated with alterations of HRV indicating an impaired cardiac autonomic control, independently of other cardiovascular risk factors.

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“…Otherwise, ABP was monitored noninvasively with photoplethysmography (Finapress 2300 -Ohmeda, The Netherlands). (14).…”

Section: Populationmentioning

confidence: 99%

“…Two other determinants of baroreflex diminution are age (5,12), and carotid atherosclerosis (13,6,(14)(15)(16).…”

Section: Introductionmentioning

confidence: 99%

Baroreflex Impairment After Subarachnoid Hemorrhage Is Associated With Unfavorable Outcome

Nasr

Gaio

Czosnyka

et al. 2018

Stroke

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The role of carotid plaque echogenicity in baroreflex sensitivity

Abstract: These findings suggest that echogenic plaques are associated with reduced baroreflex function compared with echolucent ones. Further investigation is warranted to define whether such an sBRS impairment could be responsible for cardiovascular morbidity associated with echogenic plaques.

Cited by 11 publications

References 40 publications

Carotid Artery Stenting–Induced Hemodynamic Instability

Carotid Artery Stenting–Induced Hemodynamic Instability

Association between Carotid Intima Media Thickness and Heart Rate Variability in Adults at Increased Cardiovascular Risk

Baroreflex Impairment After Subarachnoid Hemorrhage Is Associated With Unfavorable Outcome

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