The Role of Cardiovascular Magnetic Resonance Imaging in the Evaluation of Hypertrophic Cardiomyopathy

Sivalokanathan, Sanjay

doi:10.3390/diagnostics12020314

Cited by 10 publications

(21 citation statements)

References 86 publications

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“…The resolution of system (5) allows to write each element of the vector Vn(t) as a linear combination of the elements of the vector (𝒔 ̅,s(n)(t),𝑠 (𝑛) (2) (𝑡),𝑠 (𝑛) (4) (𝑡),..., 𝒔 (𝒏) (𝟐(𝒏−𝟏)) (𝒕)) (T) of dimension n+1. Let be 𝒓 ̅ 𝑖 and r(ij) (i=1,..., n; j =0,...,n-1) the coefficients of this combination:…”

Section: In Equation (3) S(n)(t) Is a Linear Combination Of The Terms...mentioning

confidence: 99%

“…In fact, many modalities are used to acquire images of the human heart. One of the least non-invasive modalities is magnetic resonance imaging MRI, a technique that allows the acquisition of functional (which enables locating the areas involved) and anatomical (which provides a realignment to correct a subject motion) images [4]. Cardiac MRI is used as a reference method that enables the detection of cardiac pathologies.…”

Section: Introductionmentioning

confidence: 99%

“…One of the least non-invasive modalities is magnetic resonance imaging (MRI), a technique that allows the acquisition of functional (which enables locating the areas involved) and anatomical (which provides a realignment to correct a subject motion) images. 4 Cardiac MRI is used as a reference method that enables the detection of cardiac pathologies. The study of the different cardiac cavities, particularly the left and right ventricles (RV), allows such detection.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ventricular segmentation and modeling using topological watershed transformation and harmonic state model

Mahmoudi

2022

Int J Imaging Syst Tech

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This paper proposes an adapted ventricular segmentation method based on topological watershed transform. Segmentation will allow spatio-temporal modeling of trajectories of the different points belonging to the borders of the ventricle using a harmonic motion model that is able to describe such motion over the entire cardiac cycle. In addition, extraction of the adopted canonical state vector and the corresponding state equations guarantees an optimal efficacy and a gradual transition from order n to order n+1. To validate the proposed approach, an intern-image base was used. Our results show a promising ability to discern whether subjects are healthy or pathological with an 80% success rate.

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Section: In Equation (3) S(n)(t) Is a Linear Combination Of The Terms...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ventricular segmentation and modeling using topological watershed transformation and harmonic state model

Mahmoudi

2022

Int J Imaging Syst Tech

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“…Although echocardiography is widely used to assess cardiac structure and function, cardiac magnetic resonance (CMR) has been recommended as the gold standard in the assessment of HCM due to its high spatial resolution, good image quality, and ability to identify the morphological variants of HCM (12). CMR is also a reference technique for measuring LV volume, EF, and LV mass (13).…”

Section: Introductionmentioning

confidence: 99%

Impaired cardiac pump function assessment with normalized cardiac power using cardiac magnetic resonance in patients with hypertrophic cardiomyopathy

Li¹,

Gao²,

Zhang³

et al. 2023

Quant Imaging Med Surg

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Background: Cardiac power (CP; CP = 0.222 × cardiac output × mean blood pressure) output in patients with heart failure has been studied previously, but its importance in patients with hypertrophic cardiomyopathy (HCM) remains unclear. The present study aimed to explore the role of normalized CP (normalized CP = CP/ventricle mass) in assessing cardiac function in patients with HCM with normal ejection fraction using cardiac magnetic resonance (CMR).Methods: This cross-sectional study enrolled 99 patients with HCM who underwent CMR from December 2020 to January 2022 at Beijing Anzhen Hospital, and these patients were classified into heart failure or non-heart failure subgroups. Meanwhile, a control group comprising 65 gender-and age-matched healthy volunteers was also enrolled. The baseline clinical characteristics and cardiac functional parameters were compared between the patients with HCM and the controls, and multivariable linear regression analysis was performed to analyze the relationship between normalized CP and the relevant factors.Results: Significantly higher CP (1.19 vs. 1.01 W; P=0.03) but lower normalized CP (0.73 vs. 1.12 W/100 g; P<0.001) were found in patients with HCM as compared with the controls. Multivariable analysis showed that HCM correlated well with normalized CP [β=−0.235; 95% confidence interval (CI): −0.341 to −0.129; P<0.001]. In the HCM group, there were 34 cases with heart failure and 65 with non-heart failure, and the patients with HCM with heart failure showed similar CP (1.14 vs. 1.24 W; P=0.06) but significantly lower normalized CP (0.54 vs. 0.78 W/100 g; P<0.001). The correlation analysis of normalized CP and functional parameters revealed that normalized CP was inversely correlated with left ventricle mass/body surface area

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“…Although echocardiography is usually used to assess HOCM, it may miss some hypertrophic segments and underestimate the extent of hypertrophy in the basal anterolateral wall due to limited echocardiographic windows [ 3 ]. Owning to its high resolution delineation of hypertrophy, cardiovascular magnetic resonance imaging (CMRI) has been shown to provide precise and reproducible assessment of the LV mass (LVM) and volumes [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Papillary and Trabecular Muscles Have Substantial Impact on Quantification of Left Ventricle in Patients with Hypertrophic Obstructive Cardiomyopathy

Yang

Qiao

et al. 2022

Diagnostics

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Patients with obstructive hypertrophic cardiomyopathy (HOCM) have large papillary and trabecular muscles (PTMs), which are myocardial tissue. PTMs are usually excluded from the myocardium and included in the left ventricular (LV) cavity when determining LV mass (LVM) and volumes using cardiac magnetic resonance (CMR). This conventional method may result in large distortion of LVM and other indices. We investigated 74 patients with HOCM undergoing CMR imaging. LV short-axis cine images were obtained. LV contours were drawn using two different methods: (1) the conventional method, where PTMs were included in the LV cavity; and (2) the mask method, which includes the TPMs in the LV myocardium. The LV end-diastolic volume (LV-EDV), LV end-systolic volume (LV-ESV), LV ejection fraction (LVEF), and the LVM were then calculated. Fasting NT-proBNP and CK-MB levels were measured with ELISA. In patients with HOCM, mass of PTMs (MOPTM) was 47.9 ± 18.7 g, which represented 26.9% of total LVM. Inclusion of PTMs with the mask method resulted in significantly greater LVM and LVM index (both p < 0.0001) in comparison with those measured with the conventional method. In addition, the mask method produced a significant decrease in LV-EDV and LV-ESV. LVEF was significantly increased with the mask method (64.3 ± 7.9% vs. 77.2 ± 7.1%, p < 0.0001). MOPTM was positively correlated with BMI, septal wall thickness, LVM, LV-EDV, and LV-ESV. LVEF was inversely correlated with MOPTM. In addition, MOPTM correlated positively with NT-proBNP (r = 0.265, p = 0.039) and CK-MB (r = 0.356, p = 0.002). In conclusion, inclusion of PTMs in the myocardium has a substantial impact on quantification of the LVM, LV-EDV, LV-ESV, and LVEF in patients with HOCM. The effects of the PTMs in women was greater than that in men. Furthermore, the MOPTM was positively associated with NT-proBNP and CK-MB. The PTMs might be included in the myocardium when measuring the LV volumes and mass of patients with HOCM. At present, the clinical and prognostic meaning and relevance of the PTMs is not clear and should be further studied.

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The Role of Cardiovascular Magnetic Resonance Imaging in the Evaluation of Hypertrophic Cardiomyopathy

Cited by 10 publications

References 86 publications

Ventricular segmentation and modeling using topological watershed transformation and harmonic state model

Ventricular segmentation and modeling using topological watershed transformation and harmonic state model

Impaired cardiac pump function assessment with normalized cardiac power using cardiac magnetic resonance in patients with hypertrophic cardiomyopathy

Papillary and Trabecular Muscles Have Substantial Impact on Quantification of Left Ventricle in Patients with Hypertrophic Obstructive Cardiomyopathy

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