The role of Candida species in peri-implant diseases

Smojver, Igor; Vuletić, Marko; Sušić, Mato; Marković, Luka; Pelivan, Ivica; Gabrić, Dragana

doi:10.35841/1836-1935.13.3.98-105

Cited by 3 publications

(4 citation statements)

References 61 publications

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“…C. albicans is one of the many fungal species present in the oral microbiome as a commensal and a major pathogen in oral and systemic candidiasis [ 18 ]. It also plays an important role in biofilm arrangement [ 1 ]. As a part of colonising bacterial microbiota, S. aureus is commonly associated with failed dental implants [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

“…Continuous improvements in implant design, surgical protocols, and the development of biologically oriented materials have turned implantology into predictable therapy with a high success rate of 90% [ 1 ]. Two-piece implant systems consist of the fixture or the implant itself and a prosthodontic abutment which is connected to the implant [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Efficacy and Permeability of Various Sealing Materials in Two Different Types of Implant–Abutment Connections

Smojver¹,

Bjelica

Vuletić

et al. 2022

IJMS

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The presence of a microgap along an implant–abutment connection (IAC) is considered the main disadvantage of two-piece implant systems. Its existence may lead to mechanical and biological complications. Different IAC designs have been developed to minimise microleakage through the microgap and to increase the stability of prosthodontic abutments. Furthermore, different sealing materials have appeared on the market to seal the gap at the IAC. The purpose of this study was to evaluate the antimicrobial efficacy and permeability of different materials designed to seal the microgap, and their behaviour in conical and straight types of internal IACs. One hundred dental implants with original prosthodontic abutments were divided into two groups of fifty implants according to the type of IAC. Three different sealing materials (GapSeal, Flow.sil, and Oxysafe gel) were applied in the test subgroups. The contamination of implant–abutment assemblies was performed by a joint suspension containing Candida albicans and Staphylococcus aureus. It was concluded that the IAC type had no significant influence on microleakage regarding microbial infection. No significant difference was found between the various sealing agents. Only one sealing agent (GapSeal) was found to significantly prevent microleakage. A complete hermetic seal was not achieved with any of the sealing agents tested in this study.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antimicrobial Efficacy and Permeability of Various Sealing Materials in Two Different Types of Implant–Abutment Connections

Smojver¹,

Bjelica

Vuletić

et al. 2022

IJMS

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“…Significantly higher counts of S. aureus and S. anaerobius were detected in implants with peri-implantitis when compared to those of healthy implants [15]. The oral microbiome has more than 100 fungal species, and C. albicans plays an important role in the formation and stabilization of biofilm, consequently enabling the development of peri-implant mucositis and peri-implantitis [16]. In addition, C. albicans and S. aureus are rarely associated with periodontal disease, but possess the ability to attach themselves to titanium surfaces [17].…”

Section: Discussionmentioning

confidence: 99%

Sealing Efficacy of the Original and Third-Party Custom-Made Abutments—Microbiological In Vitro Pilot Study

Smojver¹,

Bjelica

Ćatić

et al. 2022

Materials

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Implant–abutment connection (IAC) is a key factor for the long-term success and stability of implant-supported prosthodontic restoration and its surrounding tissues. Misfit between prosthodontic abutment and implant at the IAC leads to technical and biological complications. Two kinds of prosthodontic abutments are currently available on the market: original and third-party abutments. The aim of this pilot study was to test and compare the internal fit (gap) at the implant–abutment interface depending on the abutment fabrication method based on microbial leakage in static conditions and the need for the use of gap sealing material. Two groups of 40 implants were formed on the basis of the type of abutment. In each of the groups of two implant systems, two subgroups of 10 implants were formed. The tested subgroups consisted of 10 implants with sealing material and a negative control subgroups consisting of 10 implants without any sealing material. The test material, GapSeal (Hager and Werken, Duisburg, Germany) was applied in the test subgroups. The implant–abutment assemblies were contaminated with a solution containing Staphylococcus aureus and Candida albicans for 14 days under aerobic conditions. Results showed that there was no statistically significant difference regarding the microbial leakage between the original and third-party custom-made abutments, regardless of the use of sealing material. It can be concluded that the abutment fabrication method has no significant influence on sealing efficacy regarding the bacterial and fungal leakage in static conditions.

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“…Recent research has focused on the association between peri-implantitis and mycobiome since peri-implant diseases are related to the oral microbiome. The most prominent oral fungus, Candida albicans, seems to play a significant role in the development of periimplant pockets due to the development of a biofilm on titanium surfaces, which permits the growth of pathogenic bacteria [46].…”

Section: Peri-implantitis and Oral Mycobiomementioning

confidence: 99%

Oral Mycobiota: A Narrative Review

Defta,

Albu,

Albu

et al. 2024

Dentistry Journal

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Numerous studies have proven the important role of the oral microbiota in health and disease. The dysfunctionality of the oral microbiota, known as dysbiosis, is incriminated in dental caries, periodontal disease, oral infectious diseases, oral cancer, and systemic disease. The lesser-known component of the oral microbiota, the mycobiota, is now assiduously investigated. Recent technological developments have helped foster the identification of new fungal species based on genomic research. Next-generation sequencing has expanded our knowledge about the diversity, architecture, and relationships of oral microorganisms within the oral cavity. The mycobiome structure and relationships with the bacteriome have been studied to identify a mycobiotic signature. This review aimed to emphasize the latest knowledge of the oral mycobiome.

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The role of Candida species in peri-implant diseases

Cited by 3 publications

References 61 publications

Antimicrobial Efficacy and Permeability of Various Sealing Materials in Two Different Types of Implant–Abutment Connections

Antimicrobial Efficacy and Permeability of Various Sealing Materials in Two Different Types of Implant–Abutment Connections

Sealing Efficacy of the Original and Third-Party Custom-Made Abutments—Microbiological In Vitro Pilot Study

Oral Mycobiota: A Narrative Review

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