The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L

Ashraf, Asma; Ijaz, Muhammad Umar; Muzammil, Saima; Nazir, Mohammad; Zafar, Saima; Zihad, S. M. Neamul Kabir; Uddin, Shaikh Jamal; Hasnain, Md Saquib; Nayak, Amit Kumar

doi:10.1016/j.fitote.2023.105612

Cited by 11 publications

(6 citation statements)

References 53 publications

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“… 16 It has also shown pharmacological activities, including wound healing, analgesic, hemostatic, antioxidant, and diuretic effects. 17 As a natural food color, annatto serves as a viable substitute for artificial food colorants. Annatto seeds are highly popular as a global natural dye, widely used in industries such as food, textiles, paint, and cosmetics.…”

Section: Introductionmentioning

confidence: 99%

Sustainable appraisal of lipstick tree seeds (Bixa orellana)-based bixin natural orange colorant for green mordanted silk fabrics and wool yarns

Yameen,

Adeel,

Salman

et al. 2024

Science Progress

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This research aims to optimize the silk and wool dyeing process using natural dyes from Bixa orellana (annatto) through response surface methodology. Central composite design experiments highlight the significant enhancement of color outcomes achieved through microwave treatment. For silk, the optimal conditions (80 °C for 40 min) with annatto extract yield a color strength (K/S) of 17.8588, while wool achieves a K/S of 7.5329. Introducing eco-friendly bio-mordants, such as pomegranate peel and red sumac tannins, enhances color strength. Pre-dyeing treatments with 2% red sumac, 1.5% pomegranate peel, and weld flower extracts for silk produce high color strength, with K/S values of 16.4063, 16.3784, and 12.1658, respectively. Post-dyeing, the K/S values increase to 40.1178, 17.4779, and 21.6494. Wool yarn exhibits similar improvements, with pre-dyeing K/S values of 13.1353, 13.5060, and 16.3232, escalating to 10.5892, 15.3141, and 23.4850 post-dyeing. Furthermore, this research underscores improved colorfastness properties, including notable enhancements in light, wash, and rubbing fastness for both silk fabric and wool yarn. These findings underscore the efficacy of the proposed sustainable dyeing methods, offering valuable insights for eco-friendly textile production.

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Section: Introductionmentioning

confidence: 99%

Sustainable appraisal of lipstick tree seeds (Bixa orellana)-based bixin natural orange colorant for green mordanted silk fabrics and wool yarns

Yameen,

Adeel,

Salman

et al. 2024

Science Progress

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“…It can also reduce proinflammatory cytokines by blocking the TLR4/NF‐B pathway. Carotenoids like bixin are capable of scavenging free oxygen radicals, which helps in curing (Ashraf et al., 2023 ).…”

Section: Introductionmentioning

confidence: 99%

“…Carotenoids like bixin are capable of scavenging free oxygen radicals, which helps in curing (Ashraf et al, 2023).…”

mentioning

confidence: 99%

Study on synergistic effects of curcumin and bixin against foodborne pathogens

Hosseini,

Habibi Najafi,

Rasool Oromiehie

et al. 2024

Food Science & Nutrition

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Various studies have shown that natural colorants, in addition to their coloring attributes, have valuable biological effects such as antioxidant, anti‐inflammation, and anticarcinogenic properties. Moreover, their use as a food colorant can restrict the potential disadvantages of synthetic additives and turn foods into functional products. In this study, in vitro antimicrobial activities of two natural colorants of bixin and curcumin against some important foodborne pathogens: Staphylococcus aureus (S. aureus), Listeria innocua (L. innocua), and Escherichia coli (E. coli) were investigated by disk diffusion method. Minimum inhibitory concentration and minimum bactericidal concentration values were determined by agar dilution and broth microdilution methods. The synergistic activity of the colorants against selected microorganisms was assayed by the checkerboard microdilution method. The results showed that the inhibitory effects of bixin against S. aureus were more pronounced than E. coli and L. innocua. The lowest concentration of curcumin (0.6 mg/mL) in the disk diffusion method was not inhibited by any tested bacteria. However, it was effective at the higher concentrations against three microorganisms, but its diameter of inhibition zones was lower than gentamicin in all concentrations. Synergetic effects were observed by curcumin and bixin combination against S. aureus (FICI ≤ 0.5), but they act as an antagonist against E. coli and L. innocua. The results of the synergy test were confirmed by the isobologram curves.

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“…The pigment extracted from its seeds is commercially referred to as annatto, typically used as a spice and dye, providing a yellow-orange hue to various food products [14,15]. Besides that, it is approved as a colorant and additive by the Food and Drug Administration (FDA) and can be extracted using one or a suitable combination of food-grade solvents, such as acetone, ethylene dichloride, hexane, isopropyl alcohol, methyl alcohol, methylene chloride, and trichloroethylene [16,17]. Additionally, it exhibits various beneficial health properties, including antioxidant effects [18], antimicrobial activity [19], potential anticancer properties [20], anti-inflammatory properties [21], and nephroprotective activity [22].…”

Section: Introductionmentioning

confidence: 99%

“…Bixin (C 25 H 30 O 4 ) constitutes 80% of the annatto seed extract and is composed of an open chain of 25 carbons with a methyl ester and a carboxylic group at the end [17]. To analyze annatto, specifically bixin, various detection techniques are used, including ultraviolet (UV), and mass spectrometry (MS), in conjunction with liquid chromatography (LC) [23].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Bixin by UV-Visible Spectroscopy and HPLC, and Its Application as Latent Fingermark Developer

Bueno,

Leitzke,

Crizel

et al. 2024

Analytica

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Fingerprints are essential for human identification and are valuable tools in criminal investigations. The pursuit of new materials for digital printing is expanding, with increasing interest in natural compounds such as bixin, sourced from annatto seeds. Despite its traditional use as a natural dye with medicinal properties, the potential of bixin in papilloscopy remains largely untapped. In this study, we meticulously extracted bixin from annatto seeds and meticulously developed composites incorporating zinc carbonate (bixin/ZnCO3) and kaolinite (bixin/kaolinite). UV-visible spectroscopy was used for characterization, and the extracted bixin showed absorption peaks at 429, 453, and 481 nm, which were very similar to standard peaks at 429, 457, and 487 nm. The two samples also had the same retention times (7.07 min) according to further liquid chromatography analysis. Sweat pores were easier to detect thanks to the effectiveness of the bixin/ZnCO3 and bixin/kaolinite composites in creating high contrast sebaceous and natural latent fingerprints. These results highlight the composites’ potential as novel and fascinating instruments for papilloscopy applications, which might also improve forensic investigations.

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The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L

Cited by 11 publications

References 53 publications

Sustainable appraisal of lipstick tree seeds (Bixa orellana)-based bixin natural orange colorant for green mordanted silk fabrics and wool yarns

Sustainable appraisal of lipstick tree seeds (Bixa orellana)-based bixin natural orange colorant for green mordanted silk fabrics and wool yarns

Study on synergistic effects of curcumin and bixin against foodborne pathogens

Characterization of Bixin by UV-Visible Spectroscopy and HPLC, and Its Application as Latent Fingermark Developer

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