The role of bile acid receptor TGR5 in regulating inflammatory signalling
Daijiao Ye,
Jiayao He,
Xiaofei He
Abstract:Takeda G protein‐coupled receptor 5 (TGR5) is a bile acid receptor, and its role in regulating metabolism after binding with bile acids has been established. Since the immune response depends on metabolism to provide biomolecules and energy to cope with challenging conditions, emerging evidence reveals the regulatory effects of TGR5 on the immune response. An in‐depth understanding of the effect of TGR5 on immune regulation can help us disentangle the interaction of metabolism and immune response, accelerating… Show more
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