The Role of Beta-Lactamase-Producing Bacteria in Obstetrical and Gynecological Infections

Abstract

Pelvic inflammatory disease (PID) is a polymicrobial infection that evolves multiple aerobic and anaerobic bacteria. Several of the bacterial pathogens that participate in PID can produce the enzyme beta lactamase. These include Bacteroides species (including Bacteroides bivius, Bacteroides disiens, and Bacteroides fragilis group), Neisseria gonorrheae,Enterobacteriaceae and Staphylococcus aureus. A recent increase in numbers of beta-lacta-mase-producing strains of these organisms in PID has been associated with increased failure rates of penicillins in eradication of this infection. These organisms cannot only survive penicillin therapy but also protect penicillin-susceptible pathogens from the drug. These direct and indirect virulence characteristics of beta-lactamase-producing bacteria require the administration of appropriate antimicrobial therapy directed against all of these pathogens in the therapy of PID.

A Comparative Study of Chemical Composition of Acacia Seyal Stem, Stem Wood and Stem Bark Dry Distillates Used by Sudaneses Women as Cosmetic and Medicine

“…The present paper represents the first attempt to investigate and compare of the content and composition of the dry distillates (Dokhan) of A. seyal stem, stem wood and stem bark with potent antioxidant and antimicrobial activities [1] which is traditionally used by Sudanese women for cosmetic and therapeutic purposes mainly for the treatment of candidiasis, genital yeast infection, urinary tract infection, severe stomach cramps, diarrhea, vomiting, respiratory tract disease, cold and throat infection, wound and skin infection and toothache [1,11].…”