The role of b1 methylation, physiologic replication independent endogenous dna double strand breaks (phy-rind-edsb) and laminin 511 e8 proteins in rat second degree burn wound healing
Jiraroch Meevassana
Abstract:Background: DNA methylation via short interspersed nuclear element (SINE) small interfering (si)RNA prevents DNA damage and promotes cell proliferation. Furthermore, laminin ?5 ?1 ?1(LM511) is an extracellular structural protein that can support epithelial cell adhesion and migration. Box A of high-mobility group box 1 protein (Box A of HMGB1) is a common nuclear protein in eukaryotic cells that can reduce DNA damage response toward burn injury.
Objective: To investigate whether treatment of burn … Show more
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