The role of autophagy in Parkinson’s disease: a gender difference overview
Laura Cucinotta,
Deborah Mannino,
Alessia Filippone
et al.
Abstract:Recent studies have demonstrated dysregulation of the autophagy pathway in patients with Parkinson’s disease (PD) and in animal models of PD, highlighting its emerging role in disease. In particular, several studies indicate that autophagy, which is an essential degradative process for the damaged protein homeostasis and the management of cell balance, can manifest significant variations according to gender. While some evidence suggests increased autophagic activation in men with PD, women may have distinct re… Show more
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