The Households having low socio-economic status possess less resource in term of wealth and income to resist against any kind of external shocks. Apart from heath shocks (physical and mental disabilities) there are numerous other factors that force them to follow subsistence life style having low per capita income. A primary level data has been collected to examine the socio economic status of households in Southern Punjab for the year 2019.The findings show that household size, occupation, dependency ratio, mental disability and physical disability are negatively affecting economic development across the region. However, age, education of the household head, own house, spouse ‘s participation, remittances, number of earners in the household and value of physical assets are increasing economic development in Southern Punjab. Developing strategies, adequate planning and their timely implementation is very crucial for the government to pursue the process of economic growth and development of the poor countries like Pakistan.