The Role of Antioxidant Supplementation in Endometriosis Therapy

Sinha, Annika

doi:10.19080/jgwh.2017.03.555601

Cited by 7 publications

(7 citation statements)

References 11 publications

(19 reference statements)

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“…Vitamins E (alpha-tocopherol) and C, have differences in the contribution they make to antioxidant potential, as vitamin E is the major lipid soluble chain-breaking antioxidant in cellmembranes while vitamin C is an important aqueous phase antioxidant. Antioxidants may act synergistically, for instance when vitamin C regenerates alpha-tocopherol from the tocopherol radical [25,26] This 'sacrificial' antioxidant acts more by sparing vitamin E than by recycling [25,10]. Thus, it might be important to evaluate the effectiveness of potential antioxidant defense systems in limiting scale.…”

Section: Discussionmentioning

confidence: 99%

Study of Antioxidants Vitamin E and Ascorbic Acid level in Pre-eclampsia and Normotensive Pregnant Women Attending the Antenatal Department of a Rural Hospital in Imo State South East Nigeria

Nnamdi

Izuchukwu

Nwaisaac

et al. 2021

AJMAH

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Background: Deficiencies of nutrition are common during pregnancy especially in developing countries. Pregnant women in developing countries have been reported to consume diets that are low in minerals and vitamins. Inadequate dietary intake during pregnancy might be a high risk not only for the mother but also for the fetus. Deficiencies of antioxidant vitamins have been implicated in various reproductive disorders like infertility, congenital anomalies, pre-eclampsia, placental abruption, premature rupture of membranes, still births and low birth weight. Objective/Aim: This investigation was performed to compare the level of serum antioxidant vitamin E and Ascorbic Acid status in women with preeclampsia and normal pregnancy in Imo State. It was a randomized cross sectional study of 50 preeclampsia and 50 normotensive pregnant women attending the Dept. of Medicine and Antenatal clinic of specialist Hospital Umuguma, Owerri Imo State Nigeria. The study protocol was reviewed and the ethical committee and participants gave their consent. Data analysis was done using the statistical package for social sciences (SPSS) version 20.0. P-value of < 0.05 was considered to be statistically significant. Results: The mean antioxidant vitamins E and C were significantly lower in the preeclampsia group (0.29±0.07 and 0.31±0.20mg/dl) against the control (0.64±0.16 and 0.89±0.27mg/dl) P<0.05 respectively. Conclusion: The study showed significant decrease in the level of vitamin E and Ascorbic Acid suggesting the failure of compensatory antioxidant functions in preeclampsia women.

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Section: Discussionmentioning

confidence: 99%

Study of Antioxidants Vitamin E and Ascorbic Acid level in Pre-eclampsia and Normotensive Pregnant Women Attending the Antenatal Department of a Rural Hospital in Imo State South East Nigeria

Nnamdi

Izuchukwu

Nwaisaac

et al. 2021

AJMAH

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“…Endometriosis is associated with oxidative stress, even though the pathogenesis of the condition is currently unknown. Patient with endometriosis have an altered balance of prooxidant and antioxidant molecules [44][45][46].…”

Section: Endometriosismentioning

confidence: 99%

Role of Vitamin E in Pregnancy

Siddiqui¹,

Ahmad²,

Ali³

et al. 2021

Vitamin E in Health and Disease - Interactions, Diseases and Health Aspects

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Vitamins play important roles in female health. They are essential for many functions, including menstruation and ovulation, oocyte (egg) quality and maturation. Vitamin E was first discovered in 1922 as a substance necessary for reproduction. It has become widely known as a powerful lipid-soluble antioxidant. There are various reports on the benefits of vitamin E on health in general. Vitamin E helps your body create and maintain red blood cells, healthy skin, eyes and strengthens your natural immune system. However, despite it being initially discovered as a vitamin necessary for reproduction, to date studies relating to its effects in this area are lacking. Vitamin E supplementation may help reduce the risk of pregnancy complications involving oxidative stress, such as pre-eclampsia. This chapter is written to provide a review of the known roles of vitamin E in pregnancy.

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“…Recent evidence suggest that antioxidant supplements may reduce pelvic pain in patients with endometriosis [87,88].…”

Section: Antioxidantsmentioning

confidence: 99%