The role of antioxidant properties of Nardostachys jatamansi in alleviation of the symptoms of the chronic fatigue syndrome

Lyle, Nazmun; Gomes, Antony; Sur, Tapas Kumar; Munshi, Santanu; Paul, Suhrita; Chatterjee, Suparna; Bhattacharyya, Dipankar

doi:10.1016/j.bbr.2009.04.005

Cited by 52 publications

(36 citation statements)

References 20 publications

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“…In the present study, in order to reduce the stress resistance, we attempted to establish animal models of CFS by combined use of stress inducers such as temperature stimulation (cold water), energy consumption (swimming) as well as mental stimulation (emotional stimulation induced by electric shocks ,cold water swim and restraint stress protocol). The time required for model construction varied in the present literatures, being more than two weeks in most studies [15][16][17] . In our study, the construction time lasted 23 days.…”

Section: Animal Model Establishment and Intervention Methodsmentioning

confidence: 96%

Effects of exercise on behavior and peripheral blood lymphocyte apoptosis in a rat model of chronic fatigue syndrome

Zou

Yuan

Liu

et al. 2010

J. Huazhong Univ. Sci. Technol. [Med. Sci.]

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This study examined the effects of exercise on behavior and peripheral blood leukocyte apoptosis in a rat model of chronic fatigue syndrome (CFS). Thirty-six healthy male Sprague-Dawley rats were equally randomized into 3 groups: the control group, CFS model group and the exercise group in terms of body weight. A total of 25 rats entered the final statistical analysis due to 11 deaths during the study. CFS model was established by subjecting the rats in CFS model group and exercise group to electric shock, chronic restraint stress and cold water swim. Besides, rats in the exercise group took running wheel exercise. After a week of conditioning feeding, model construction and running wheel exercise were performed simultaneously, and lasted for 23 consecutive days. The behavior experiments, including running wheel exercise, open-field test, tail suspension test and Morris water maze test, were conducted, either before or after the model establishment. Rats were sacrificed and peripheral blood was obtained for the assessment of lymphocyte apoptosis index by flow cytometry (FCM). It was found that as compared with those in the control group, the weight of the rats was decreased obviously (P<0.01), the mobility time in the open-field and the tail suspension tests was shortened significantly (P<0.01), the time to locate the platform was enhanced (P<0.01) and the cell apoptosis index was increased substantially (P<0.01) in the CSF model group. Meanwhile, in comparison to the model group, the behavior in the open-field and the tail suspension tests was improved significantly (P<0.05), and the apoptosis index decreased remarkably (P<0.01) in the exercise group. It is concluded that sport intervention can prevent lymphocyte apoptosis and improve animal behavior rather than the memory.

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Section: Animal Model Establishment and Intervention Methodsmentioning

confidence: 96%

Effects of exercise on behavior and peripheral blood lymphocyte apoptosis in a rat model of chronic fatigue syndrome

Zou

Yuan

Liu

et al. 2010

J. Huazhong Univ. Sci. Technol. [Med. Sci.]

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show abstract

“…The total numbers of counts indicating movement of the mice were measured for 30 min and were expressed as total photocell counts of the photoactometer for 30 min per animal. Modification of locomotor function was assessed on day-7, day-8, day-9 and day-10 in control, sleep-deprived (SD), SD with ES 70 and SD with ES 280 groups (Lyle et al, 2009). …”

Section: Behavioral Testsmentioning

confidence: 99%

Bioactivity-guided fractionation for anti-fatigue property of Acanthopanax senticosus

Huang

et al. 2011

Journal of Ethnopharmacology

113

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“…Many CFS animal models were used to study the mechanism of CFS, such as mental stimulation, forced exercise, herbal drugs and restraint stress protocol (Lyle et al, 2009;Shevchuk, 2007;Zou et al, 2010). The required time for CFS model construction is always more than two weeks (Ottenweller et al, 1998;Singh, Naidu, Gupta, & Kulkarni, 2002).…”

Section: Discussionmentioning

confidence: 99%

Immunomodulating and antioxidant effects of polysaccharide conjugates from the fruits of Ziziphus Jujube on Chronic Fatigue Syndrome rats

Chi

Kang

Yan

et al. 2015

Carbohydrate Polymers

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The role of antioxidant properties of Nardostachys jatamansi in alleviation of the symptoms of the chronic fatigue syndrome

Cited by 52 publications

References 20 publications

Effects of exercise on behavior and peripheral blood lymphocyte apoptosis in a rat model of chronic fatigue syndrome

Effects of exercise on behavior and peripheral blood lymphocyte apoptosis in a rat model of chronic fatigue syndrome

Bioactivity-guided fractionation for anti-fatigue property of Acanthopanax senticosus

Immunomodulating and antioxidant effects of polysaccharide conjugates from the fruits of Ziziphus Jujube on Chronic Fatigue Syndrome rats

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