“…However, because overproduction of PPIX by marrow continues, protoporphyric hepatopathy may recur (Samuel et al, 1988;de Torres et al, 1996;Meerman et al, 1999a;Dellon et al, 2002;McGuire et al, 2005). Marrow stem cell transplantation after a temporary remission of hepatopathy or liver transplantation can prevent recurrent liver damage (Rand et al, 2006;Wahlin and Harper, 2010;Dowman et al, 2011;Wahlin et al, 2011b;Singal et al, 2014). At present, identification in advance of patients at risk for development of hepatopathy is impossible.…”