The Role and Research Progress of Drug-Resistant Oral Microorganisms in the Pathogenesis of Periodontitis

Abstract

This comprehensive paper takes a deep dive into the critical role played by drug-resistant oral microorganisms in the pathogenesis of periodontitis, along with the recent research advancements in this field. It begins by defining drug resistance and its underlying causes, delving into the various types of resistance encountered in oral microorganisms. The paper then shifts its focus to the complex pathogenesis of periodontitis, discussing how drug-resistant microorganisms contribute to the development and progression of this common oral disease. The intricate relationship between drug-resistant microorganisms and periodontitis is further explored, shedding light on how these microorganisms evade traditional antibiotic treatments and contribute to the persistence and recurrence of the disease. The paper also highlights the methodologies and cutting-edge techniques that researchers are utilizing to study this phenomenon, including advanced genomic sequencing, biofilm analysis, and animal models. The paper provides an overview of the latest research progress in this area, discussing promising new treatment strategies that are being developed to target drug-resistant microorganisms. These strategies include the use of novel antimicrobials, bacteriophage therapy, and immune-based approaches.