The Risk of Ischemic and Hemorrhagic Stroke in Patients With Idiopathic Inflammatory Myopathies: A Swedish Population‐Based Cohort Study

Abstract

Our findings indicate that the risk of both IS and HS is elevated for individuals with IIM but it should be kept in mind that stroke is a rare event. Focus on prevention should be directed towards groups with the highest absolute risk, especially older patients. This article is protected by copyright. All rights reserved.

Coronary Heart Disease and Cardiovascular Risk Factors in Patients With Idiopathic Inflammatory Myopathies: A Systemic Review and Meta-Analysis

“…Of them, nine articles (CHD, four articles; cardiovascular risk factors, five articles) were excluded due to lacking available data, and 8 articles (CHD, two articles; cardiovascular risk factors, six articles) were also excluded as they utilized the same database. For example, the study by Antovic et al (26) and the study by Moshtaghi-Svensson et al (27) used the same databases (the Swedish National Patient Register Database and the Swedish Population Register Database), but the latter reported the most comprehensive results, thus, we only included the study by Moshtaghi-Svensson et al in the current review. Finally, seven articles focused on CHD risk and nine articles focused on cardiovascular risk factors met the inclusion criteria and were included in this meta-analysis (11)(12)(13)(14)(15)(16)(17)(27)(28)(29)(30)(31)(32)(33)(34).…”

“…For example, the study by Antovic et al (26) and the study by Moshtaghi-Svensson et al (27) used the same databases (the Swedish National Patient Register Database and the Swedish Population Register Database), but the latter reported the most comprehensive results, thus, we only included the study by Moshtaghi-Svensson et al in the current review. Finally, seven articles focused on CHD risk and nine articles focused on cardiovascular risk factors met the inclusion criteria and were included in this meta-analysis (11)(12)(13)(14)(15)(16)(17)(27)(28)(29)(30)(31)(32)(33)(34). Moreover, the majority of eligible studies in the current review were about patients with DM/PM, but these studies did not describe the different subtypes of PM or DM in detail.…”

“…Only two studies fully documented three traditional cardiovascular risk factors (30,31), while the majority of studies only contained one or two cardiovascular risk factors. Furthermore, the included studies were conducted in many countries, including China (11,33,34), Canada (13,14,29), Sweden (15,16,27), United States (US) (17,28), United Kingdom (UK) (12,30), Italy (31), and Australia (32). Besides, the control group was matched according to age and gender with the case group in each study.…”

Are Thrombotic Events in Dermatomyositis Related to The Effect of Antiphospholipid Antibodies? Comment on the Article by Moshtaghi‐Svensson et al

“…The high incidence of ischemic strokes among individuals with dermatomyositis was the subject of an intriguing article by Moshtaghi‐Svensson et al , recently published in Arthritis Care & Research . The reported incidence of ischemic events is characteristic of antiphospholipid syndrome, a known association with connective tissue diseases .…”

Untitled

“…As the most flagrant manifestations of disease are most "newsworthy," lesser manifestations receive less attention and the spectrum of disease effects may not receive deserved attention. It is perhaps not surprising that antiphospholipid antibodies have been associated with increased thromboembolic events immunologic disorders such as systemic lupus erythematosus [1,3], dermatomyositis [4], scleroderma [5], rheumatoid and psoriatic arthritis [5] and vasculitis [5]. However, they are also commonly present in individuals with thromboembolic disease, including strokes and myocardial infarctions [1,2].…”