A program to control cancer of the uterine cervix in women of a low‐income level in Louisville (Jefferson County), Kentucky over a 12‐year period is described. Initial satisfactory examinations were obtained on 37,209 women. Rescreenings at an interval of 1 to 12 years totaled 51,063 examinations. The population was equally divided between Negroes and Caucasians. Prevalence rates of cytologically detected cervix carcinoma were very high—3.79 per 1000 for invasive squamous carcinoma and 4.41 for carcinoma in situ. The first repeat examination based on patient years fell to 0.67 and 1.46 per 1000 women for these 2 lesions. The decrease continued through subsequent screenings. Stage I carcinoma increased to 63.93% of the total cases during the years of screening. We conclude from the data presented that mortality rates from cervix cancer will have to reflect the decrease in incidence and the increase in early diagnosed cases.