The Rh allele frequencies in Gaza city in Palestine

Skaik, Younis

doi:10.4103/0973-6247.83241

Cited by 7 publications

(1 citation statement)

References 11 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Phenotypic profiling and assessment of allele frequencies help in evaluating the distribution of antigens in a particular population and at the same time helps in estimating the chances of getting compatible blood units for patients who have developed multiple antibodies. [ 6 ] Although large scale studies are available from European and other countries on Rh phenotypic profiling and allele frequencies, only a few studies are available from the subcontinent of India on the prevalence of Rh and Kell antigens.…”

Section: Introductionmentioning

confidence: 99%

Assessment of rhesus and kell blood group antigens, phenotypes, and their allelic frequencies in North Indian blood donors

Pahuja

Jain

Nain

et al. 2020

Asian J Transfus Sci

View full text Add to dashboard Cite

BACKGROUND: Prevalence of rhesus (Rh) and Kell antigens in a population vary with race, ethnicity, and geographical location. With advances in immunohematology, non-D antigens, and their corresponding antibodies are increasingly being found to be culprits for alloimmunization. MATERIALS AND METHODS: Assessment of the phenotype of Rh and Kell blood group antigen in the healthy donor population from North India was done, and estimation of the frequencies of these alleles in our population was performed. RESULTS: The most common antigen in the North Indian donor population was “e” (95.6%) followed by “C” (89.6%), “c” (57.7%), and “E” (17.29%) in that order. The most prevalent phenotype in the Indian population was found to be “CDe” followed by “CcDe” and “CcDEe.” “K” antigen was found to be positive in 1.81% of the population. DISCUSSION: Knowledge of the Rh antigen profiles in a given population can be very helpful in formulating transfusion guidelines specific to a particular population with an aim to minimize the cost and maximize the benefits. With this aim in mind and considering the problems encountered in developing countries like ours, we conducted Rh and Kell antigen profiling of donors. Comparative analysis with other population studies and implications for transfusion protocols is evaluated. CONCLUSION: Assessment of Rhesus antigen profile of a particular population is useful to develop cost effective ways of providing maximum benefits of blood transfusion with least resources.

show abstract

Section: Introductionmentioning

confidence: 99%

Assessment of rhesus and kell blood group antigens, phenotypes, and their allelic frequencies in North Indian blood donors

Pahuja

Jain

Nain

et al. 2020

Asian J Transfus Sci

View full text Add to dashboard Cite

show abstract

Prevalence of Rh and K phenotypes among blood donors from different ethnicities in Samtah (Southwestern Region) Saudi Arabia

Hamali

Madkhali

Dobie

et al. 2022

Int J Immunogenetics

View full text Add to dashboard Cite

Introduction: Rh and Kell blood group systems are amongst the most important blood group systems; being highly immunogenic after ABO system. The aim of this study was to evaluate the frequencies of Rh antigens, haplotypes and K antigen among blood donors belonging to various ethnicities in Samtah, Jazan, Saudi Arabia.Methods: This study was conducted during January 2019 and August 2020 at Samtah General Hospital, Samtah. Records of all blood donors recruited during this period were included for data acquisition. A total of 4977 blood donors' records were reviewed and data were analysed. A total of 3863 donors' results were considered in the final analysis.Results: In comparison to Saudi blood donors, C antigen was less frequent in Sudanese donors (69.7% and 34.0%), the c antigen was less frequent in Indian (79.2% and 59.3%) and Philippine (79.2% and 40.0%) donors and more frequent in Sudanese (79.2% and 97.9%) donors, the E antigen was less frequent in Yemini (27.0% and 19.5%) and the e antigen was more frequent in Yemini (96.7% and 99.2%) donors. The DcE haplotype was less frequent (3.1% and 0.7%) and the ce haplotype was more frequent (4.3% and 7.6%) in Yemini donors. The K antigen was less frequent in Pakistani (11.9% and 4.1%; p = .041) and Indian (11.9% and 1.9%; p = .023) donors.Conclusion: Rh and K antigens showed marked variations in their frequencies among blood donors of different ethnicities. Utilization of blood from various ethnicities warrant extended phenotyping of Rh and K antigens to avoid the risk of alloimmunization in multiply transfused patients.

show abstract

ABO, RH phenotypes and kell blood groups frequencies in an Egyptian population

Swelem¹,

Goubran²,

Younis³

et al. 2018

HTIJ

View full text Add to dashboard Cite

The Rhesus blood group system (ISBT 004) is the most complex and polymorphic blood group system; comprising 54 antigens numbered RH1 to RH61 with seven obsolete numbers. There are 18 phenotypes can be distinguished by using anti-D,C,c,E, and e. In addition, there are eight possible haplotype arrangements of Rh genes on short arm of chromosome 1 i.e. Dce, DCe, DcE, DCE, dec, dCe, dcE and dCE and results in 36 possible genotypes. 3 The KEL (Kell) system (ISBT 006) is currently known to contain 36 antigens. The K antigen is strongly immunogenic. Anti-K has been reported as the cause of hemolytic transfusion reactions, both immediate and delayed, and hemolytic disease of the newborn. 4 There is wide variation in the frequencies of ABO, Rh and Kell antigens throughout the world and there is no published data from Egypt about this issue. The aim of this study was to detect the frequencies of ABO, Rh and Kell blood group antigens among blood recipients from the inpatients and blood donors coming to Suez Canal University Hospital blood bank, Ismailia, and to compare it with that of other ethnic groups. Subjects and methodsThis observational cross-sectional study was conducted at Suez Canal University Hospital blood bank, Ismailia, Egypt. Two milliliters whole blood samples were taken into ethylenediaminetetraacetic acid (EDTA) tubes from blood donors, and inpatients who were admitted

show abstract

The Rh allele frequencies in Gaza city in Palestine

Cited by 7 publications

References 11 publications

Assessment of rhesus and kell blood group antigens, phenotypes, and their allelic frequencies in North Indian blood donors

Assessment of rhesus and kell blood group antigens, phenotypes, and their allelic frequencies in North Indian blood donors

Prevalence of Rh and K phenotypes among blood donors from different ethnicities in Samtah (Southwestern Region) Saudi Arabia

ABO, RH phenotypes and kell blood groups frequencies in an Egyptian population

Contact Info

Product

Resources

About