The revision acetabulum – allograft and bone substitutes

Jj, Callaghan; Ss, Liu; Oa, Phruetthiphat

doi:10.1302/0301-620x.96b11.34452

Cited by 11 publications

(7 citation statements)

References 17 publications

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“…Previous in vitro investigations showed that leukocyte- and platelet-rich plasma (L-PRP) gel is active against selected bacterial strains [ 6 – 8 ]. Some authors also reported clinical observations about a decreasing number of infections and the induction of healing processes after L-PRP use in orthopedics [ 9 ], trauma [ 10 ], maxillofacial [ 11 ], and cardiac surgery [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Leukocyte- and Platelet-Rich Plasma: AnIn VitroStudy

Cieślik-Bielecka¹,

Bold

Ziółkowski³

et al. 2018

BioMed Research International

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The aim of the study was to investigate the leukocyte- and platelet-rich plasma (L-PRP) antimicrobial activity. The studied sample comprised 20 healthy males. The L-PRP gel, liquid L-PRP, and thrombin samples were tested in vitro for their antibacterial properties against selected bacterial strains using the Kirby-Bauer disc diffusion method. Two types of thrombin were used (autologous and bovine). Zones of inhibition produced by L-PRP ranged between 6 and 18 mm in diameter. L-PRP inhibited the growth of Staphylococcus aureus (MRSA and MSSA strains) and was also active against Enterococcus faecalis and Pseudomonas aeruginosa. There was no activity against Escherichia coli and Klebsiella pneumoniae. The statistically significant increase of L-PRP antimicrobial effect was noted with the use of major volume of thrombin as an activator. Additionally, in groups where a bovine thrombin mixture was added to L-PRP the zones of inhibition concerning MRSA, Enterococcus faecalis, and Pseudomonas aeruginosa were larger than in the groups with autologous thrombin. Based on the conducted studies, it can be determined that L-PRP can evoke in vitro antimicrobial effects and might be used to treat selected infections in the clinical field. The major volume of thrombin as an activator increases the strength of the L-PRP antimicrobial effect.

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Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Leukocyte- and Platelet-Rich Plasma: AnIn VitroStudy

Cieślik-Bielecka¹,

Bold

Ziółkowski³

et al. 2018

BioMed Research International

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show abstract

“…Many formulations, such as ProOsteon, Osteoset (calcium sulfate ceramic), and Vitoss (tricalcium phosphate scaffold), are available; although they may be effective at least in the short term for smaller lesions, the efficacy of these materials is still largely unknown. 46 In addition, concerns exist that if this material migrated into the joint space, it could lead to third-body wear. 47 Stamenkov et al 35 used highresolution CT to follow up 22 osteolytic lesions in six patients over approximately 4 years.…”

Section: Clinical Outcomes Of Reconstructive Optionsmentioning

confidence: 99%

Evaluation and Treatment of Patients With Acetabular Osteolysis After Total Hip Arthroplasty

Sheth

Rozell

Paprosky

2019

J Am Acad Orthop Surg

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As the demand for total hip arthroplasty (THA) continues to increase, the burden of revision THA is also expected to increase. Although the quality of polyethylene has improved markedly, osteolysis continues to be a risk for older designs and younger, active patients. Although progressive but typically asymptomatic in early stages, osteolysis can result in component failure and complicate revision surgery. Serial radiographs are paramount for monitoring progression. Although select cases may be treated with observation, surgery should be considered based on age, activity level, and projected life span. Wellfixed, noncemented modular acetabular components may be treated with curettage and bone grafting, as well as having to bear liner exchange with retention of the acetabular shell. However, in the setting of osteolysis, it is controversial whether bone grafting and component retention is superior to cup revision. This review explores the pathophysiology of osteolysis after THA and provides a comprehensive analysis of the evaluation and treatment of patients with osteolysis.O steolysis after total hip arthroplasty (THA) continues to be a common cause of revision surgery. 1 As such, bearing surface wear has led to contemporary THA prosthesis designs. With the exponential increase in THA procedures being performed and the number of patients with older designs and conventional polyethylene, surgeons must understand implant properties to achieve the most favorable clinical outcomes.

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“…Sin embargo, los resultados en el uso de aloinjerto han sido variables respecto a su integración, y el subsecuente aflojamiento. 25,26 El uso de copas jumbo con cuñas metálicas para la solución de defectos osteolíticos acetabulares es actualmente la forma de revisión más empleada por cirujanos de cadera en cirugía ATC de revisión. 27 Los resultados han sido más constantes, eliminando el riesgo de reabsorción ósea en injertos y disminuyendo el riesgo de aflojamiento o falla en implantes con tasas de supervivencia de copas revisión de más de 90 a 95% a cinco años en diferentes series.…”

Section: Wwwmedigraphicorgmxunclassified

Aflojamiento aséptico en la prótesis total de cadera

Parra¹

2019

Ortho-Tips

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The revision acetabulum – allograft and bone substitutes

Cited by 11 publications

References 17 publications

Antibacterial Activity of Leukocyte- and Platelet-Rich Plasma: AnIn VitroStudy

Antibacterial Activity of Leukocyte- and Platelet-Rich Plasma: AnIn VitroStudy

Evaluation and Treatment of Patients With Acetabular Osteolysis After Total Hip Arthroplasty

Aflojamiento aséptico en la prótesis total de cadera

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