The review of versatile application of collagen

Sionkowska, Alina; Skrzyński, Sławomir; Śmiechowski, Krzysztof; Kołodziejczak, A.

doi:10.1002/pat.3842

Cited by 140 publications

(152 citation statements)

References 106 publications

(182 reference statements)

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“…Because of this, it has started to be used in fields that require high efficiency and biocompatibility. For example, in the medical field, it is often used for implants such as artificial skin grafts, wound dressings, and nerve conduits due to its low immunogenicity . Now in cosmetics, its properties take to the development of creams and gels with high moisturizing action, but other activities are also foreseen, such as anti‐aging, antiwrinkling, UV radiation protectors, and healing of wounds among other applications .…”

Section: Objectivesmentioning

confidence: 99%

“…For example, in the medical field, it is often used for implants such as artificial skin grafts, wound dressings, and nerve conduits due to its low immunogenicity . Now in cosmetics, its properties take to the development of creams and gels with high moisturizing action, but other activities are also foreseen, such as anti‐aging, antiwrinkling, UV radiation protectors, and healing of wounds among other applications . Its inclusion in cosmetic formulations has to do with its film‐forming properties, when applied covers the skin and decreases the transepidermal water loss, protecting skin from corrosive elements …”

Section: Objectivesmentioning

confidence: 99%

“…In 2016, the global collagen market (Figure ) size was estimated at USD 3.71 billion and is expected to witness an important growth over the next years, and it is anticipated to reach USD 6.63 billion by 2025. This is mainly as a result of the growing demand of beverages and food, cosmetics, and health care, among others previously mentioned; this growth can be attributed to the growing global population . The global tissue‐engineered collagen biomaterial market will likely progress at a robust CAGR (compound annual growth rate) of 10.4% during the period between 2017 and 2025 …”

Section: Objectivesmentioning

confidence: 99%

See 2 more Smart Citations

Collagen: A review on its sources and potential cosmetic applications

Rodríguez

Barroso

Sánchez

2017

J of Cosmetic Dermatology

368

213

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Summary Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. This molecule is one of the most abundant in many of the living organisms due to its connective role in biological structures. Due to its abundance, strength and its directly proportional relation with skin aging, collagen has gained great interest in the cosmetic industry. It has been established that the collagen fibers are damaged with the pass of time, losing thickness and strength which has been strongly related with skin aging phenomena [Colágeno para todo. 60 y más. 2016. http://www.revista60ymas.es/InterPresent1/groups/revistas/documents/binario/ses330informe.pdf.]. As a solution, the cosmetic industry incorporated collagen as an ingredient of different treatments to enhance the user youth and well‐being, and some common presentations are creams, nutritional supplement for bone and cartilage regeneration, vascular and cardiac reconstruction, skin replacement, and augmentation of soft skin among others [J App Pharm Sci. 2015;5:123‐127]. Nowadays, the biomolecule can be obtained by extraction from natural sources such as plants and animals or by recombinant protein production systems including yeast, bacteria, mammalian cells, insects or plants, or artificial fibrils that mimic collagen characteristics like the artificial polymer commercially named as KOD. Because of its increased use, its market size is valued over USD 6.63 billion by 2025 [Collagen Market By Source (Bovine, Porcine, Poultry, Marine), Product (Gelatin, Hydrolyzed Collagen), Application (Food & Beverages, Healthcare, Cosmetics), By Region, And Segment Forecasts, 2014 – 2025. Grand View Research. http://www.grandviewresearch.com/industry-analysis/collagen-market. Published 2017.]. Nevertheless, there has been little effort on identifying which collagen types are the most suitable for cosmetic purposes, for which the present review will try to enlighten in a general scope this unattended matter.

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Section: Objectivesmentioning

confidence: 99%

Section: Objectivesmentioning

confidence: 99%

Section: Objectivesmentioning

confidence: 99%

See 1 more Smart Citation

Collagen: A review on its sources and potential cosmetic applications

Rodríguez

Barroso

Sánchez

2017

J of Cosmetic Dermatology

368

213

View full text Add to dashboard Cite

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“…Other properties of CLG are anti‐aging and anti‐wrinkling; hence, CLG has been developed as a component of moisturizers or humectants for the skin . In human skin, CLG is synthesized by fibroblasts as procollagen, which is converted to a collagen molecule (the main type being type 1 CLG, 85–90%) . Recently, collagen hydrolysate (CGH) having considerably lower molecular weight than CLG has been frequently used instead of CLG for the same purpose as it can be absorbed more efficiently.…”

Section: Introductionmentioning

confidence: 99%

“…5 In human skin, CLG is synthesized by fibroblasts as procollagen, which is converted to a collagen molecule (the main type being type 1 CLG, 85-90%). 6 Recently, collagen hydrolysate (CGH) having considerably lower molecular weight than CLG has been frequently used instead of CLG for the same purpose as it can be absorbed more efficiently. CLG is generally obtained from fish scale and the skin of pig and cow.…”

Section: Introductionmentioning

confidence: 99%

Viscosity Effects of Hydrophilic Polymers on Transport of Collagen Hydrolysate Across Reconstructed Human Buccal Tissue

Koo

Lee

Yeo

et al. 2020

Bulletin Korean Chem Soc

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Herein we investigate the influence of hydrophilic polymers on the buccal permeability of collagen hydrolysate (CGH) by performing in vitro buccal permeation test and viscosity measurements. After we demonstrated that CGH (2000–3000 Da) could be delivered across the reconstructed human buccal tissue as evaluated by hydroxyproline assay, the effects of different hydrophilic polymers, varying amounts of CGH, and hydration methods were examined to elucidate the relationship with buccal permeation behavior of CGH. The percentage of CGH permeated was found to be highest in HPMC E5 solution and greater when the viscosity of test solutions was low. Using commercially obtained CGH‐loaded buccal films, the films under higher hydration condition exhibited greater CGH permeation. This study demonstrates that CGH can be delivered via the human buccal tissue and viscosity of the solution significantly affects the CGH permeation. These findings are valuable for designing hydrophilic polymer‐based buccal film formulations for peptides like CGH.

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Biodegradable Polymers for Biomedical and Tissue Engineering

Pushpamalar

Paramasivam

Meganathan

et al. 2020

Materials Science and Technology

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Currently, scientists are on the cutting edge of inventing many novel biomaterials from various sources for selection in tissue engineering and controlled drug delivery systems to improvise the patient surgical and treatment processes. This article focuses on the significant improvements made in the design of natural, biodegradable polymer‐based biomaterials and their applications in biomedical and tissue engineering areas. Polysaccharide and protein‐based hydrogels are suitable for soft and hard biomaterials. The soft biomaterial is made of biodegradable natural or synthetic or in a combination of both polymers that can be utilized for a stipulated time and cleared partly or whole of the system that it treats, enhance the rate of healing or replace tissues or organs. Soft biomaterials fabricated for muscle, ligament, tendon, articular cartilage tissue engineering exhibit valuable properties, such as biocompatibility, biodegradability, flexible, renewability, and cheaper. The combination of the polysaccharides and proteins with synthetic biodegradable polymers improved the mechanical strength and when added with inorganic calcium compounds could be exploited in hard tissue engineering, such as bone tissue engineering. The development of biomaterial for scaffolding in tissue engineering using polysaccharides and proteins could lead to the emergence of a new era of safer material to replace the damaged tissues in the body without suffering inflammation. Polysaccharides and proteins are consumed as food, and treating damaged tissue with food‐based biomaterial would not harm the humankind. In the near future, the development of natural polymer‐based biodegradable biomaterials by interdisciplinary and multidisciplinary research scientists is highly important.

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The review of versatile application of collagen

Cited by 140 publications

References 106 publications

Collagen: A review on its sources and potential cosmetic applications

Collagen: A review on its sources and potential cosmetic applications

Viscosity Effects of Hydrophilic Polymers on Transport of Collagen Hydrolysate Across Reconstructed Human Buccal Tissue

Biodegradable Polymers for Biomedical and Tissue Engineering

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