Abstract:The reverse planning method was used in the author's center in more than 500 cases of deformity correction and lower extremity lengthening using the Fitbone intramedullary lengthening nail, but the planning and surgical principles are applicable to lengthening and deformity correction with other intramedullary straight devices or for "lengthening over a nail" procedures.
“…It is estimated that each 1-cm length gain is coupled with ∼1 mm lateral mechanical axis deviation [41]. Reverse planning method may be useful in this situation [42].…”
External fixators are a well-established modality for treating fractures with bone defects, leg-length discrepancy, malunion, nonunion and other post-traumatic consequences. However, use of internal lengthening rods has remarkably increased recently for post-traumatic conditions. The main advantage of internal lengthening rods is eliminating pin-site complications. Internal lengthening rods are also associated with less pain. Motorised internal lengthening rods show promising performance in post-traumatic cases. Rigorous pre-operative planning is paramount to reducing lengthening-related complications. Certain types of internal lengthening rods offer bidirectional movement capability. Nail mechanism malfunction is a possibility with all kinds of nails. Direct doctor supervision is required, especially in the initial stages while the nail is lengthening. Internal lengthening nails are not as stiff as regular nails, with intricate internal mechanisms that can be broken under inattentive weightbearing activities. Preliminary positive outcomes indicate the role of internal lengthening rods in treating posttraumatic problems of leg-length discrepancy, malunion and nonunion.
“…It is estimated that each 1-cm length gain is coupled with ∼1 mm lateral mechanical axis deviation [41]. Reverse planning method may be useful in this situation [42].…”
External fixators are a well-established modality for treating fractures with bone defects, leg-length discrepancy, malunion, nonunion and other post-traumatic consequences. However, use of internal lengthening rods has remarkably increased recently for post-traumatic conditions. The main advantage of internal lengthening rods is eliminating pin-site complications. Internal lengthening rods are also associated with less pain. Motorised internal lengthening rods show promising performance in post-traumatic cases. Rigorous pre-operative planning is paramount to reducing lengthening-related complications. Certain types of internal lengthening rods offer bidirectional movement capability. Nail mechanism malfunction is a possibility with all kinds of nails. Direct doctor supervision is required, especially in the initial stages while the nail is lengthening. Internal lengthening nails are not as stiff as regular nails, with intricate internal mechanisms that can be broken under inattentive weightbearing activities. Preliminary positive outcomes indicate the role of internal lengthening rods in treating posttraumatic problems of leg-length discrepancy, malunion and nonunion.
“…However, requiring multiple pins and involving an invasive surgically created fracture, this procedure is riddled with issues such as pin site infections and lengthy lengthening time. More recently, another bone lengthening procedure using an internally implanted nail called 'Fitbone' is being utilised (Baumgart 2009), but it can only be used in adults. Furthermore, bone angulation deformities are often treated via the insertion of various interpositional materials following the surgical removal of bony repair tissue at the growth plate injured site.…”
Section: Current Corrective Treatments For Growth Plate Injuriesmentioning
Injuries to the growth plate cartilage often lead to bony repair, resulting in bone growth defects such as limb length discrepancy and angulation deformity in children. Currently utilised corrective surgeries are highly invasive and limited in their effectiveness, and there are no known biological therapies to induce cartilage regeneration and prevent the undesirable bony repair. In the last 2 decades, studies have investigated the cellular and molecular events that lead to bony repair at the injured growth plate including the identification of the four phases of injury repair responses (inflammatory, fibrogenic, osteogenic and remodelling), the important role of inflammatory cytokine tumour necrosis factor alpha in regulating downstream repair responses, the role of chemotactic and mitogenic platelet-derived growth factor in the fibrogenic response, the involvement and roles of bone morphogenic protein and Wnt/B-catenin signalling pathways, as well as vascular endothelial growth factor-based angiogenesis during the osteogenic response. These new findings could potentially lead to identification of new targets for developing a future biological therapy. In addition, recent advances in cartilage tissue engineering highlight the promising potential for utilising multipotent mesenchymal stem cells (MSCs) for inducing regeneration of injured growth plate cartilage. This review aims to summarise current understanding of the mechanisms for growth plate injury repair and discuss some progress, potential and challenges of MSC-based therapies to induce growth plate cartilage regeneration in combination with chemotactic and chondrogenic growth factors and supporting scaffolds.
“…Furthermore, in contrast to lengthening with external fixation—which usually follows the mechanical axis—lengthening over a straight intramedullary nail occurs along the nail axis, which typically approaches the anatomical axis [18]. Thus, even in patients without angular deformities, changes of the mechanical axis are inevitable during the lengthening process (e.g.…”
Section: General Considerations Of Intramedullary Leg Lengthening Andmentioning
confidence: 99%
“…certain degree of valgisation in retrograde femur lengthening). If this geometry-caused axis shift is not taken into account preoperatively, intramedullary lengthening might result in an iatrogenic axis deformity [18]. Therefore, lengthening with/without concomitant angular deformities using straight implants always necessitates a thorough preoperative planning, as well as a thorough implantation technique [18, 19].…”
Section: General Considerations Of Intramedullary Leg Lengthening Andmentioning
Unlike external fixators, the use of solid intramedullary lengthening nails is restricted to defined anatomical preconditions, such as an adequate bone length. Furthermore, all deformity corrections except the lengthening procedure have to be implemented intraoperatively and cannot be adjusted postoperatively. Conversely, even complex deformity corrections can be performed using intramedullary devices after a thorough preoperative planning. For preparation of the intramedullary cavity as well as positioning of the lengthening nail according to the preoperative planning, reaming the medullary canal with rigid reamers which don’t follow the line of least resistance is inevitable. However, the application of solid lengthening nails might be limited, especially in children with ongoing epiphyseal growth, although a central perforation of the growth plate was shown to have no adverse effects on the growth potential. In cases with complex or multilevel deformities, an additional osteotomy and locking plate fixation could sometimes be a valuable solution in order to avoid external fixation. The low complication rate as well as the reduced compromising of soft tissues and periosteum render intramedullary lengthening nails the state-of-the-art procedure for limb lengthening in combination with deformity correction in patients who meet the anatomical preconditions.
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