The resurgence of acute bronchiolitis cases after the declaration of the end of state of emergency

Rius-Peris, Juan Manuel; Vázquez, Carlos Marcilla; Menchón, Natalia Molini; Almira, Elena Felipe; Beneyto, Raúl Silvestre

doi:10.1016/j.anpede.2022.01.004

Cited by 1 publication

(3 citation statements)

References 6 publications

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“…Other factors that may be related to this finding could be the larger percentage of patients older than 3 months admitted during the pandemic period, who generally have better outcomes 31 and would have been discharged sooner. However, we do not have a definite explanation for the shorter LOS found in our sample, although other studies have reported similar findings 36 …”

Section: Discussioncontrasting

confidence: 90%

“…However, we do not have a definite explanation for the shorter LOS found in our sample, although other studies have reported similar findings. 36 Prematurity is a known risk factor for prolonged LOS in children with viral respiratory infections, 31,37,38 which was significant in the multivariable analysis of both periods in our sample. In a recent metaanalysis, 31 a younger age at admission-below 3 months-has the highest odds ratio for poor outcomes in children with RSV acute lower respiratory tract infection, which is consistent with our findings.…”

Section: Discussionmentioning

confidence: 73%

“…To our knowledge, this is the only large single-center study in Spain to have analyzed the epidemic patterns and risk factors for adverse events in the first complete bronchiolitis season after the loosening of pandemic restrictions and make a detailed comparison with research from our group in previous years. 15,17 Other authors have looked at the temporal trends 20 and clinical characteristics in smaller hospitals 9,23,36 until the 2021 summer outbreak. and duration of prophylaxis [42][43][44][45] and to select the ideal timing to conduct clinical trials.…”

Section: Discussionmentioning

confidence: 99%

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Bronchiolitis before and after the SARS‐CoV‐2 pandemic: Twelve years of experience in a Spanish paediatric hospital

Guerrero-del-Cueto

Ramos-Fernández

Leiva-Gea

et al. 2023

Pediatric Pulmonology

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Introduction Acute bronchiolitis is the main cause of hospitalization in children under 2 years of age, with a regular seasonality, mostly due to the respiratory syncytial virus. Objectives To describe the epidemiology of bronchiolitis hospitalizations in our center in the last 12 years, and analyze the changes in clinical characteristics, microbiology, and adverse outcomes during the SARS‐CoV‐2 pandemic. Methods Observational study including patients admitted for bronchiolitis between April 2010 and December 2021 in a Spanish tertiary paediatric hospital. Relevant demographic, clinical, microbiological, and adverse outcome variables were collected in an anonymized database. The pandemic period (April 2020 to December 2021) was compared to 2010−2015 seasons using appropriate statistical tests. Results There were 2138 bronchiolitis admissions, with a mean of 195.6 per year between 2010 and 2019 and a 2−4‐month peak between November and March. In the expected season of 2020, there was a 94.4% reduction of bronchiolitis hospitalizations, with only 11 cases admitted in the first year of the pandemic. Bronchiolitis cases increased from the summer of 2021 during a 6‐month long peak, reaching a total of 171 cases. Length of stay was significantly shorter during the pandemic, but no differences were found in clinical and microbiological characteristics or other adverse outcomes. Conclusions The SARS‐CoV‐2 pandemic has modified the seasonality of bronchiolitis hospitalizations, with a dramatic decrease in cases during the expected season of 2020−2021, and an extemporaneous summer−autumn peak in 2021 with longer duration but similar patient characteristics and risk factors.

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Section: Discussioncontrasting

confidence: 90%