The results of VEN/frequency analysis of pharmacotherapy of patients with chronic gastroduodenitis in a healthcare institution of Kharkiv

Gerasymova, O. O.; Ovsienko, Ye. V.

doi:10.24959/sphhcj.18.112

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Наданню ефективної медичної допомоги й медикаментозному забезпеченню хворих на хронічний гастрит і дуоденіт приділялась увага в дослідженнях вітчизняних учених [1,5]. Однак комплексних клініко-економічних досліджень, присвячених оптимізації медикаментозного забезпечення хворих на ХГ військовослужбовців із застосуванням вісмутвмісної схеми із включенням вітчизняного рабепразолу та ВТД в Україні не проводилось.…”

Section: вступunclassified

Prevalence, clinical course and treatment of chronic gastritis at the present stage

Osyodlo

Kotyk

Kalashnikov³

et al. 2021

GASTRO

View full text Add to dashboard Cite

Background. The importance of the problem of chronic gastritis (CG) is determined by its high proportion in the structure of gastrointestinal pathology, reduced quality of life of patients, and possible complications. The study aimed at the investigation of the incidence and features of the clinical course of CG in servicemen at the present stage and pharmacoeconomic efficacy of bismuth and triple anti-helicobacter therapy (AHBT) in H. pylori (HP) — associated erosive gastritis with the use of domestic drugs. Materials and methods. At the first stage, the indicators of the admission rate of servicemen with CG and the peculiarities of the endoscopic picture of the gastric mucosa were analyzed. At the second stage, the features of the clinical course were studied and a pharmacoeconomic analysis of treatment regimens in servicemen with HP-associated erosive gastritis with proton pump inhibitors of different generations and domestic bismuth subcitrate, used in triple and bismuth-containing regimens, was performed. Results. An epidemiological, clinical, and pharmacoeconomic analysis of HP-associated CG in servicemen at the present stage has been conducted. It is reasonable to treat servicemen with HP-associated erosive gastritis with domestic drugs using bismuth-containing anti-helicobacter therapy, which will improve the efficiency and quality of treatment and avoid unjustified budget costs. Conclusions. Among the servicemen of the Armed Forces of Ukraine, starting from 2013, there is a tendency to increase the number of erosive gastroduodenal lesions with a predominant lesion of the antrum of the stomach. Pharmacoeconomic analysis of the treatment of HP-associated erosive gastritis showed the feasibility of switching to bismuth-containing AHBT with the use of domestic rabeprazole and bismuth subcitrate. This is justified by a higher anti-Helicobacter activity by 1.2 times (20 %), 1.6 times better (60 %) cost-effectiveness, and 1.4 times higher (40 %) cost-utility.

show abstract

Section: вступunclassified