The Results of a 3-year Clinical Trial of Pravastatin

Ryu, Tomiko; Matsusaki, Tadashi; Yamanaka, Takeshi; Kainuma, Akira; Kamei, Siro; Kabuki, Keiichiro; Kaburaki, Keinosuke; Takatsuki, Katsuyoshi; Fukui, Tsuguya; Tatemichi, Masayuki; Nagoshi, Hisao; Narazaki, Masahiko; Nomura, Takayoshi; Hara, Koichiro; Fukuo, Yoshihiro; Mitsuyama, Hiroshi; Mori, Kousuke; Naito, Chikayuki

doi:10.5551/jat1973.24.1-2_61

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2005

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“…Indeed, these results are in line with similar changes in lipid profiles observed with 3 years' pravastatin therapy that have previously been reported in Japan. 44 The aim of the present study was to clarify the treatment effect of pravastatin in Japanese patients. QCA was chosen as the primary endpoint because of the large sample size that would have been required for a clinical endpoint study in a population at low risk of cardiovascular events.…”

Section: Discussionmentioning

confidence: 99%