The responses of injured and noninjured rat periodontal tissues to a single administration of dihydrotachysterol

Stahl, S. S.; Epstein, Bernard S.

doi:10.1016/0030-4220(67)90548-8

Cited by 1 publication

(2 citation statements)

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“…In rats given DHT, enlargement of buccal and lingual bone occurred most notably at muscle insertions [95]. Alveolar bone formation at the site of a gingival injury took place more rapidly and was more evident in experimentally injured than noninjured rats that also received DHT [96]. Similarly, mineralization of the periodontal ligament and gingival connective tissue was enhanced when a collagendamaging agent was given to rats receiving intraperitoneal injections of vitamin D 2 [97].…”

Section: Role Of Local Traumamentioning

confidence: 99%

“…10-16) have been reported [91,[95][96][97][98][99][100][101][102]104,[106][107][108][109][110][111][112][113][114][115][116][117][118][119][120][121][122][123][124][125]. Extrapolating these findings to the domestic cat should be done with caution, however, because the results of these experimental studies are not uniform.…”

Section: Experimental Studies With Vitamin D and Vitamin D Metabolitesmentioning

confidence: 99%

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Update on the Etiology of Tooth Resorption in Domestic Cats

Reiter

Lewis

Okuda

2005

Veterinary Clinics of North America: Small Animal Practice

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Feline odontoclastic resorptive lesions (FORL) were first recognized and histologically differentiated from caries in the 1920s [1,2]. Some anecdotal reports describing caries-like lesions at the cervical region of feline teeth followed in the 1950s and 1960s, until two microscopic studies in the 1970s again revealed that FORL were not caries but a type of tooth resorption [3,4]. A recent study showed that cats with FORL have a significantly lower urine specific gravity and significantly higher serum concentration of 25-hydroxyvitamin D (25OHD) compared with cats without FORL [5], indicating that multiple tooth resorption in domestic cats could be the manifestation of some systemic insult rather than a local cause. In this article, the histologic and radiographic appearance of FORL and certain other peculiarities of feline teeth are reviewed. An attempt is then made to compare these findings with changes of the periodontium induced by administration of excess vitamin D or vitamin D metabolites in experimental animals. Histologic and radiographic features of feline odontoclastic resorptive lesionsTooth resorption is caused by odontoclasts. Their precursors derive from hematopoietic stem cells of bone marrow or spleen and migrate from blood vessels of the alveolar bone or periodontal ligament toward the external root

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Section: Role Of Local Traumamentioning

confidence: 99%