The response of alanine to a 150keV X-ray beam

Zeng, Guanggen; McCaffrey, J. P.

doi:10.1016/j.radphyschem.2004.05.044

Cited by 29 publications

(22 citation statements)

References 8 publications

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“…¼16, P « 0.0001). Similar effect has been seen by Waldeland et al (2010) and Zeng and McCaffrey (2005). As suggested by them, we can explain this difference based on two factors, those related to radiation physics and radiation chemistry.…”

Section: Resultssupporting

confidence: 80%

“…The radiation chemistry relates to the generation of stable free radicals in alanine for these two radiation qualities. Same amount of absorbed energy produces about 6% fewer stable free radicals in alanine for X radiation as compared to Cobalt-60 gamma radiation due to higher LET of the X radiation (Zeng and McCaffrey, 2005). Combining these two effects result in about 21% reduction in alanine-EPR response for 60 keV X radiation as compared to cobalt-60 gamma radiation, for the same dose to water.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Alanine-EPR as a transfer standard dosimetry system for low energy X radiation

Khoury

Silva

Mehta³

et al. 2015

Radiation Physics and Chemistry

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Section: Resultssupporting

confidence: 80%

Section: Resultsmentioning

confidence: 99%

Alanine-EPR as a transfer standard dosimetry system for low energy X radiation

Khoury

Silva

Mehta³

et al. 2015

Radiation Physics and Chemistry

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“…In previous studies of alanine exposed to x rays, the measured energy responses were well below unity at low x-ray energies ͑20-40 keV͒ and converged toward unity for energies above 100 keV. 10,[27][28][29][30]34,35,40 However, in several of the publications, the information on x-ray beam qualities employed ͑e.g., HVL͒ is not adequate. The term effective energy used in this work refers to the energy of a monoenergetic beam with the same HVL as the x-ray beam employed.…”

Section: Discussionmentioning

confidence: 99%

“…Upon irradiation of alanine with particles of high linear energy transfer ͑LET͒, a significant reduction in radiation yield relative to that following low LET 60 Co ␥-irradiation is seen for neutrons, protons, and heavier ions. 33 Furthermore, one theoretical 34 and one experimental 35 study have indicated that the radiation yield in alanine following irradiation with medium energy x rays also is reduced relative to that following low LET 60 Co ␥-irradiation. A dependence of the radiation yield on radiation quality is also expected for lithium formate.…”

Section: Introductionmentioning

confidence: 99%

The energy dependence of lithium formate and alanine EPR dosimeters for medium energy x rays

et al. 2010

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“…It is well known that alanine sensitivity to photon energies below 100 keV is reduced about 30 -40% in relation to 60 Co energy (1.25 MeV) (Regulla and Deffner 1982;Zeng and McCaffrey 2005;Lund et al 2002). Previous work reported an enhanced sensitivity of alanine to low-energy x-rays through mixing it with potassium iodine (KI) (Chen et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Sensitivity Comparison of Two L-Alanine Doped Blends to Different Photon Energies

Chen¹,

Ramirez²,

Nicolucci³

et al. 2010

Health Physics

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Blends of L-alanine (85% weight proportion) with KI (10%) and with PbI2 (10%), these last two compounds acting as dopants, and with PVA (5%) acting as binder, were prepared in water at 80 degrees C. A blend of pure L-alanine (95%) with PVA (5%) was also prepared. The three blends were irradiated with photon beams of different energies (120 kV, Co, and 10 MV) to a unique dose of 30 Gy to compare their sensitivities for those three energies. EPR spectra of the three irradiated blends were recorded in a K-Band spectrometer (24 GHz) taking aliquots of about 4 mg for each blend. The energy sensitivity of a blend was defined as the peak-to-peak amplitude of its EPR spectrum central line. For the Co energy (1.25 MeV) the blends presented practically the same sensitivity, indicating that the presence of the dopants does not affect the sensitivity of L-alanine. For 10 MV x-rays, there was an increment (around 10%-20%) in sensitivity for the two L-alanine doped blends compared with the pure L-alanine blend (not doped). In the case of 120 kV x-rays, the blends ala+KI and ala+PbI showed increments of 10 and 20 times more sensitivity than the pure L-alanine blend. It is concluded that the dopants KI and PbI2 produce a great enhancement of the L-alanine sensitivity to low-energy photons. For the same dopant's content (10%) in the blend, PbI2 showed a better performance. Increasing the PbI2 proportion (30%) in the blend allows the detection of radiation dose as low as 10 mGy for 120 kV x-rays. These results encourage the authors to try to enhance the sensitivity of L-alanine even more by increasing the dopant's content in the blend and diminishing the lower limit detection. Application of these L-alanine doped blends in the dosimetry in diagnostic radiology could be possible.

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The response of alanine to a 150keV X-ray beam

Cited by 29 publications

References 8 publications

Alanine-EPR as a transfer standard dosimetry system for low energy X radiation

Alanine-EPR as a transfer standard dosimetry system for low energy X radiation

The energy dependence of lithium formate and alanine EPR dosimeters for medium energy x rays

Sensitivity Comparison of Two L-Alanine Doped Blends to Different Photon Energies

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