The resistance of maxillofacial reconstruction plates to biofilm formation in vitro

Emery, Brian E.; Dixit, Rahul; Formby, C. Craig; Biedlingmaier, John F.

doi:10.1097/00005537-200311000-00023

Cited by 6 publications

(2 citation statements)

References 18 publications

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“…In vitro results have reported that bacterial cells exhibit reduced adhesion to titanium and resorbable polylactide plates, which is attributed to the surface charge and smoothness. 154 This reduced adhesion is also consistent with the reduced incidence of infection in case of patients who received implants made of these materials.…”

Section: Substrate Characteristicssupporting

confidence: 73%

Characteristics of bacterial biofilm associated with implant material in clinical practice

Venkatesan

Chittaranjan

Kurian

et al. 2012

Polym J

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Colonization of bacteria around native host cells or polymeric implant surfaces results in a dense growth on the surface, which leads to infection. The change of a bacterium from a motile planktonic to a nonmotile long chain of growing cells is a complex, regulated process that depends on several factors. The probability of a biofilm-related infection occurrence is between 65 and 80%. This review critically evaluates the mode of biofilm formation on native tissues and orthopedics, dental, cardiac, and urological implants and vascular grafts. The combination of biochemical advancements with conventional microbiological techniques and the use of radio-labeled monoclonal antibodies in imaging techniques, with recent developments in the detection of these biofilm in vivo, would help in designing biomaterials that prevent bacterial adhesion and biofilm formation, and dislodge the formed biofilm, thereby accelerating the product development phase.

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Section: Substrate Characteristicssupporting

confidence: 73%

Characteristics of bacterial biofilm associated with implant material in clinical practice

Venkatesan

Chittaranjan

Kurian

et al. 2012

Polym J

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“…The chemical composition of the substratum plays an important role in bacterial adhesion to medical devices [2]. The physical properties of the biomaterial surface, such as roughness, hydrophobicity, surface energy, and electrostatic charge, also affect this process, especially in metallic materials [3,4]. Inorganic material surfaces are hydrophilic, display high surface energy, and frequently carry negative charge, whereas polymers such as ultra‐high molecular weight polyethylene (UHMWPE) are considered to be hydrophobic, with low surface energy and low electrostatic charge [1].…”

Section: Introductionmentioning

confidence: 99%

Effect of surface roughness and sterilization on bacterial adherence to ultra-high molecular weight polyethylene

Kinnari

Esteban²,

Zamora³

et al. 2010

Clinical Microbiology and Infection

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Sterilization with ethylene oxide (EO) and gas plasma (GP) are well-known methods applied to ultra-high molecular weight polyethylene (UHMWPE) surfaces in the belief that they prevent major material changes caused by gamma irradiation. However, the influence of these surface sterilization methods on bacterial adherence to UHMWPE is unknown. UHMWPE samples with various degrees of roughness (0.3, 0.8 and 2.0 μm) were sterilized with either GP or EO. The variations in hydrophobicity, surface free energy and surface functional groups were investigated before and after sterilization. Sterilized samples were incubated with either Staphylococcus aureus or Staphylococcus epidermidis in order to study bacterial adherence to these materials. Fewer bacteria adhered to UHMWPE after sterilization with EO than after sterilization with GP, especially to the smoothest surfaces. No changes in chemical composition of the UHMWPE surface due to sterilization were observed using X-ray photoemission spectroscopy analysis. The decreased bacterial adherence to UHMWPE found at the smoothest surfaces after sterilization with EO was not directly related to changes in chemical composition. Increased bacterial adherence to rougher surfaces was associated with increased polar surface energy of EO-sterilized surfaces.

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Negative Pressure Wound Therapy for the Treatment of Complex Spinal Wounds

Cheng

Nasser

Staarmann

et al. 2018

Burns, Infections and Wound Management

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The resistance of maxillofacial reconstruction plates to biofilm formation in vitro

Abstract: The absence of biofilm formation on these implants can best be explained by the surface charge or polarity properties of these materials. These findings are consistent with the relatively low incidence of infections among patients receiving these implants in maxillofacial applications.

Cited by 6 publications

References 18 publications

Characteristics of bacterial biofilm associated with implant material in clinical practice

Characteristics of bacterial biofilm associated with implant material in clinical practice

Effect of surface roughness and sterilization on bacterial adherence to ultra-high molecular weight polyethylene

Negative Pressure Wound Therapy for the Treatment of Complex Spinal Wounds

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