The Residual Syntax Score for Mortality Risk Assessment in Acute Coronary Syndrome With Cardiogenic Shock

Adachi, Hidenori; Yasuoka, Yoshinori; Kaneda, Kiyoshi; Hattori, Satoshi; Noda, Yoshiki; Araki, Ryo; Matsutera, Ryo; Kosugi, Motohiro; Kohama, Yasuaki; Nakashima, Tetsufumi; Sasaki, Tatsuya

doi:10.1016/s0735-1097(13)60021-2

Cited by 4 publications

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“…[26][27][28] Our results are consistent with data drawn from the allcomers SYNTAX trial and other cohort studies, which confirm the prognostic role of rSS in patients with stable coronary artery disease, ACS, and cardiogenic shock. [4][5][6][26][27][28][29] However, they add relevant information assessing the specific and incremental role of residual coronary artery disease in elderly patients with ACS, evaluated throughout the decision curves analysis. This approach has recently been considered the best to describe and compare different prediction models, AIC, Akaike information criterion; BMI, body mass index; bSS, baseline SYNTAX score; CI, confidence interval; HR, hazard ratio; MI, myocardial infarction; rSS, residual SYNTAX score; SE, standard error; STEMI, STelevation myocardial infarction.…”

Section: Discussionmentioning

confidence: 99%

Residual SYNTAX Score and One-Year Outcome in Elderly Patients With Acute Coronary Syndrome

et al. 2020

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Background: The residual burden of coronary artery disease after percutaneous coronary intervention (PCI) has been associated with worse ischemic outcome. However, data are conflicting in elderly patients. The aim of our study was to verify the incremental value of the residual Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) score (rSS) over clinical variables and baseline SYNTAX score (bSS) in predicting 1-year mortality or cardiovascular events. Methods: A post hoc analysis of data collected in the Elderly-ACS 2 multicenter randomized trial was performed. We included 630 patients aged > 75 years with multivessel coronary disease undergoing CJC Open 2 (2020) 236e243

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Section: Discussionmentioning

confidence: 99%

Residual SYNTAX Score and One-Year Outcome in Elderly Patients With Acute Coronary Syndrome

et al. 2020

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“…patients with STEMI and multivessel disease. 44 In addition, the rSS has been shown to be a predictor of short-term adverse clinical outcomes (30-day and 6-month all-cause death) in patients with ACS complicated by cardiogenic shock 45…”

Section: Apex-ami Risk Scorementioning

confidence: 99%

Risk Stratification in Patients with Coronary Artery Disease: a Practical Walkthrough in the Landscape of Prognostic Risk Models

Buccheri

D’Arrigo

Franchina

et al. 2018

Interventional Cardiology Review

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Although a combination of multiple strategies to prevent and treat coronary artery disease (CAD) has led to a relative reduction in cardiovascular mortality over recent decades, CAD remains the greatest cause of morbidity and mortality worldwide. A variety of individual factors and circumstances other than clinical presentation and treatment type contribute to determining the outcome of CAD. It is increasingly understood that personalised medicine, by taking these factors into account, achieves better results than “one-size-fitsall” approaches. In recent years, the multiplication of risk scoring systems for CAD has generated some degree of uncertainty regarding whether, when and how predictive models should be adopted when making clinical decisions. Against this background, this article reviews the most accepted risk models for patients with evidence of CAD to provide practical guidance within the current landscape of tools developed for prognostic risk stratification.

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Prognostic Value of Residual Coronary Artery Lesions on the SYNTAX Scale in Patients with Acute Myocardial Infarction without SТ Segment Elevation in the Mid-Term Period

et al. 2021

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Aim To study the effect of residual coronary injury after a percutaneous coronary intervention (PCI), as evaluated with the SYNTAX scale (residual SYNTAX score, RSS), on the mid-term prognosis for patients with non-ST elevation acute myocardial infarction (NSTEMI) and also to determine threshold RSS values for patients at high and low risk of adverse cardiac events.Material and methods A single-center, retrospective study was performed. From 421 patients with NSTEMI after PCI with stenting, 169 patients were selected who originally had multivessel coronary disease and who had undergone a repeated inpatient examination, including mid-term (11.7±3.0 mos.) coronary angiography. The endpoints were recurrent clinical manifestations of angina, repeat revascularization (RR), unstable angina (UA), recurrent acute myocardial infarction (AMI), cardiac death, and also a composite endpoint (major adverse cardiac events, MACE) that included UA, recurrent AMI, and cardiac death. After revealing a significant direct correlation between RSS and the probability of recurrent AMI, UA, MACE, or RR (p <0.05) using the ROC analysis, we have established threshold RSS values that divided patients into groups with high and low risk of the cardiac events listed above.Results For a significantly high risk of recurrent AMI (area under the curve, AUC 0.79±0.05; 95 % confidence interval, CI 0.68–0.89; р=0.048), the threshold RSS score was 8 (sensitivity 100 %, specificity 70.9 %). For UA and MACE, the RSS scores were both 3 (AUC 0.68±0.5; 95 % CI 0.58–0.79; p=0.005 and AUC 0.71±0.05; 95 % CI 0.61–0.8; p=0.001, respectively). The probability of UA during the observation period with RSS >3 was 4.07 times higher and that of MACE was 5.23 times higher than with RSS<3 (95 % CI 1.44–11.49; р=0.01 and 95 % CI 1.88–14.53; р=0.001, respectively).Conclusion The study demonstrated a significant, direct correlation between the RSS and the risk of adverse cardiac events in patients with NSTEMI during one year of observation. Specific threshold values were obtained, which may help in choosing both the extent of revascularization and the tactics for postoperative management of patients.

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The Residual Syntax Score for Mortality Risk Assessment in Acute Coronary Syndrome With Cardiogenic Shock

Cited by 4 publications

References 0 publications

Residual SYNTAX Score and One-Year Outcome in Elderly Patients With Acute Coronary Syndrome

Residual SYNTAX Score and One-Year Outcome in Elderly Patients With Acute Coronary Syndrome

Risk Stratification in Patients with Coronary Artery Disease: a Practical Walkthrough in the Landscape of Prognostic Risk Models

Prognostic Value of Residual Coronary Artery Lesions on the SYNTAX Scale in Patients with Acute Myocardial Infarction without SТ Segment Elevation in the Mid-Term Period

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