The research gap in chronic paediatric pain: A systematic review of randomised controlled trials

Abstract

There is a substantial research gap regarding analgesic interventions for children and adolescents with chronic pain. Most clinical trials in the field focus on the evaluation of non-pharmacological interventions and are of low methodological quality. There is also a specific lack of trials involving infants and children and adolescents with long-lasting diseases.

<p>Nonpharmacological Interventions Addressing Pain, Sleep, and Quality of Life in Children and Adolescents with Primary Headache: A Systematic Review</p>

“…40 A recent systematic review by Bouhklied et al on RCTs on chronic pain in children supports this finding. 64 This is consistent with previous findings from studies with adults. 65 Blinding of participants to a nonpharmacological intervention is challenging.…”

Turn off pain evaluates the quality of pain care provided for paediatric inpatients

“…There is also a need to share protocols, organisational models and data, in order to improve paediatric pain management. Moreover, shared efforts will enable researchers to perform well‐designed studies in this setting, as previously advocated . We believe that the Turn Off Pain projects represent an important step in this direction.…”

“…This includes hospital settings . Poor pain control is partly due to the poor methodology of clinical trials conducted to date , but mostly to suboptimal standardisation and self‐evaluation of intrahospital procedures to monitor and treat pain in paediatric patients. Moreover, training for healthcare professionals on managing pain in paediatric patients is limited .…”

Analgosedation of Newborns in the Intensive Care Unit. How to Deal With Pain Syndrome

“…Щодо ефективного знеболення, то на сьогодні для новонароджених у наявності досить незначна кількість фармакологічних та нефармакологічних методів, дозволених до застосування, на відміну від знеболення у дітей старшого віку та дорослих [10,11] Матеріали та методи дослідження. Було проведене когортне проспективне дослідження, до якого увійшли 20 доношених новонароджених з больовим синдромом після тривалого оперативного втручання з приводу вродженої кишкової непрохідності.…”