The reproducibility of binocular pattern reversal visual evoked potentials: a single subject design

Abstract

This study aimed to investigate the within-participant variability over time of both amplitude and peak latency measures of pattern reversal visual evoked potentials (pVEPs). As a large number of factors are known to contribute to the variability of the pVEPs (such as fixation instability and drowsiness), testing was conducted in controlled conditions with two co-operative participants. PVEPs were recorded during 24 sessions, over an eight-week period using the same equipment and recording settings. The participants viewed a plasma monitor binocularly from a distance of 1 meter. High contrast (97%), black and white checks of side subtense 50', 25', and 12.5' pattern reversed 3/s in a 28 degree test field. The different sized checks were presented in a pseudo-random order. Three runs, each of 100 trials, were acquired to each stimulus from an active electrode placed at Oz referred to aFz. The amplitude of N80-P100 and the latency of P100 were measured. P100 amplitude and latency were stable across sessions and did not depend upon the order of check size presentation. As expected, variation in amplitude was greater than peak latency. The coefficients of variation for different check sizes and participants were 9-14% for pVEP amplitude, but only 1-2% for P100 latency.

Serial, Visually-Evoked Potentials for the Assessment of Visual Function in Patients with Craniosynostosis

“…A minimum of two reproducible trials were recorded for each stimulus. Reproducibility was determined using the criteria obtained from a previous study [14]. The two trials were deemed reproducible if the amplitude did not vary more than 15% and latency by 2%.…”

The clinical value of the multi-channel PVEP and PERG in the diagnosis and management of the patient with pituitary adenoma: a case report

“…According to the guidelines in the literature, for all measured parameters in PVEP and PERG, the intersession variability determined by calculating the coefficients of variation (CV) does not exceed 10% [ 17 ]. The CV for different check size and participants were 9–14% for PVEP amplitude, but only 1–2% for P100-wave latency [ 18 ]. The CV for PERG is 9 ± 1% [ 19 ].…”

Sport-Related Concussion and Sensory Function in Young Adults

“…44,45 Specifically, the P1 elicited by this paradigm is less variable than the P1 components elicited by other paradigms, making it preferable for evaluating clinical populations. 40 46 evaluating binocular reproducibility in a single participant, observed test-retest coefficients of variation of 9% to 14% for P1 amplitude and 1% to 2% for P1 latency.…”