The reliability of three depression rating scales in a general population of Dutch older persons

RESUMOIntrodução: A estimulação cerebral profunda (ECP) é eficaz na doença de Parkinson (DP) avançada, melhorando sintomas motores, flutuações e a qualidade de vida. No entanto, têm sido reportados efeitos adversos psiquiátricos, mas de uma forma variável e não padronizada. O objectivo deste artigo é analisar e sumarizar a evidência publicada sobre sintomas depressivos e ansiedade em doentes com DP após ECP, através de revisão sistemática e meta-análise. Material e Métodos: A PubMed foi pesquisada até Maio 2012 para identificar os estudos que avaliaram sintomas depressivos e ansiedade em doentes com doença de Parkinson submetidos a estimulação cerebral profunda bilateral do núcleo subtalâmico (NST) ou globo pálido interno (GPi). Foram feitas meta-análises com modelo de efeitos aleatórios para grupos de pelo menos três estudos homogéneos em relação ao desenho e instrumentos utilizados. Resultados: Foram selecionadas 63 referências; 98,4% continham dados relativos a escalas de avaliação de depressão e 38,1% relativos a ansiedade. Dois estudos não discriminavam o alvo usado; nos restantes 61 foi feita avaliação de curto prazo em 37 (60,7%), de médio prazo em 36 (59,0%) e de longo prazo em 5 (8,2%). Foram encontrados dados sobre variação pré/pós operatória em 57 (93,4%) estudos e 16 (26,2%) continham dados comparando ECP-NST versus outros grupos: ECP-GPi (n = 4 estudos, 25,0%), elegíveis para cirurgia (n = 6, 37,5%), e tratamento médico (n = 7, 43,8%). Discussão: É aparente a melhoria de depressão e ansiedade após ECP, sobretudo a curto prazo, efeito que tende a esbater-se em avaliações posteriores. Em relação à depressão a ECP-NST mostrou-se superior ao tratamento médico, mas não em comparação com o grupo de controlo elegível para cirurgia. Verificou-se o resultado oposto para a ansiedade, uma vez que os resultados favorecem o tratamento médico sobre a ECP-NST, e esta sobre o grupo de elegíveis para cirurgia. Não é evidente a superioridade de um alvo sobre o outro, mas os dados favorecem ligeiramente o GPi para ambos os tipos de sintomas. Conclusões:O padrão e curso dos sintomas depressivos e ansiedade após ECP na DP não são claros, mas ambos parecem melhorar no curto prazo, especialmente a depressão após a ECP-NST. Os resultados são bastante heterogéneos. Devem ser promovidos esforços no sentido de haver padronização de procedimentos de avaliação nos vários centros. Palavras-chave: Doença de Parkinson; Estimulação Cerebral Profunda; Ansiedade; Depressão; Meta-Análise. ABSTRACT Introduction: Deep brain stimulation (DBS) is effective in advancedParkinson's disease (PD), improving motor symptoms, fluctuations and quality of life. However, adverse psychiatric outcomes have been reported, albeit variably and in an unstandardized fashion. We aimed to summarize the published evidence on the outcomes of anxiety and depressive symptoms in Parkinson's disease patients following DBS, through systematic review and meta-analysis. Material and Methods: PubMed was searched until May 2012 to identify studies assessing anxiety and...

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“…Test-retest coefficients have been collected for the several psychometric instruments. [79][80][81][82][83][84][85][86][87][88][89][90] …”

Section: Methodsmentioning

confidence: 99%

Depression and Anxiety Following Deep Brain Stimulation in Parkinson’s Disease: Systematic Review and Meta-Analysis

et al. 2014

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“…Exploration of the psychometric properties showed a high internal consistency, moderate test-retest correlations and substantial evidence of construct validity [25]. The psychometric properties of the Dutch translation showed favorable results [24,26,27]. …”

Section: Methodsmentioning

confidence: 99%

“…Total scores range from 0 to 15, with higher scores indicating more depressive symptoms. A recent study showed limited reliability of this version compared to other measures of depression in a nonclinical elderly population [24]. …”

Section: Methodsmentioning

confidence: 99%

Validation of the Amsterdam IADL Questionnaire©, a New Tool to Measure Instrumental Activities of Daily Living in Dementia

et al. 2013

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Background: This study describes the validation of a new instrument measuring instrumental activities of daily living (IADL), the Amsterdam IADL Questionnaire© (a registered copyright of the Alzheimer Center of the VU University Medical Center). This informant-based tool aimed at detecting IADL problems in incipient dementia was previously found to have a high internal consistency and test-retest reliability. Methods: Patients and their informants who visited the Alzheimer Center of the VU University Medical Center were included in this study. Item response theory was used to estimate the individuals' trait levels as a measure of IADL disability. Construct validity was tested by correlating estimated trait levels with clinical and demographic measures using Pearson's or Kendall's τ correlation coefficients. Additionally, estimated trait levels between patients with and without dementia and between patients with early- and late-onset dementia were compared using independent t tests. Results: A total of 206 informants of patients completed the Amsterdam IADL Questionnaire. The correlations between estimated trait levels and other measures were in concordance with previously formed hypotheses. Patients diagnosed with dementia (n = 93) had higher estimated trait levels than patients without dementia (n = 96), Cohen's effect size, d = 1.04, t(187) = 7.1, p < 0.001. We found no differences between early- and late-onset dementia patients. Conclusions: Results suggest that the Amsterdam IADL Questionnaire is a reliable and valid instrument in the evaluation of dementia.

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“…Thus, we could only study recent symptoms of depression and did not have information about how long the depressive symptoms lasted. However, as we describe previously, the CES-D has been widely used in epidemiological studies, has demonstrated excellent reliability (Gonzalez et al, 2017; Shinar et al, 1986; van de Rest et al, 2010) and validity (Radloff, 1977), and appears to be a robust measure of depressive symptoms in Hispanic/Latino populations (Gonzalez et al, 2017). Future genetic studies of lifetime depressive disorder in Hispanic/Latino samples are warranted.…”

Section: Discussionmentioning

confidence: 95%

“…It was also shown in the current study population to have excellent internal consistency reliability (Cronbach’s alphas = .80–.86), test-retest reliability ( rs = .41–.70), and moderate to high correlations with other measures of depressive or mental health symptoms, including the Spielberger State-Trait Anxiety Inventory ( r = .72, p < .001), the Patient Health Questionnaire-9 ( r = .80, p < .001), and the Short Form-12’s Mental Component Summary ( r = −.65, p < .001) (Gonzalez et al, 2017). While the inter-rater reliability of CES-D-10 has not previously been assessed, the full 20-item CES-D has demonstrated good-to-excellent inter-rater reliability ( rs = .67–.76) (Shinar et al, 1986; van de Rest, van der Zwaluw, Beekman, de Groot and Geleijnse, 2010). Total depressive symptoms scores were calculated by summing responses to each item; item responses ranged from 0 = rarely or none of the time (< 1 day) to 3 = all of the time (5–7 days).…”

Section: Methodsmentioning

confidence: 98%

Genome-wide association study of depressive symptoms in the Hispanic Community Health Study/Study of Latinos

Dunn¹,

Sofer²,

Wang³

et al. 2018

Journal of Psychiatric Research

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Although genome-wide association studies (GWAS) have identified several variants linked to depression, few GWAS of non-European populations have been performed. We conducted a genome-wide analysis of depression in a large, population-based sample of Hispanics/Latinos. Data came from 12,310 adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Past-week depressive symptoms were assessed using the 10-item Center for Epidemiological Studies of Depression Scale. Three phenotypes were examined: a total depression score, a total score modified to account for psychiatric medication use, and a score excluding anti-depressant medication users. We estimated heritability due to common variants false(hSNP2false), and performed a GWAS of the three phenotypes. Replication was attempted in three independent Hispanic/Latino cohorts. We also performed sex-stratified analyses, analyzed a binary trait indicating probable depression, and conducted three trans-ethnic analyses. The three phenotypes exhibited significant heritability ( hSNP2=6.3−6.9normal%; p = .002) in the total sample. No SNPs were genome-wide significant in analyses of the three phenotypes or the binary indicator of probable depression. In sex-stratified analyses, seven genome-wide significant SNPs (one in females; six in males) were identified, though none were supported through replication. Four out of 24 loci identified in prior GWAS were nominally associated in HCHS/SOL. There was no evidence of overlap in genetic risk factors across ancestry groups, though this may have been due to low power. We conducted the largest GWAS of depression-related phenotypes in Hispanic/Latino adults. Results underscore the genetic complexity of depressive symptoms as a phenotype in this population and suggest the need for much larger samples.

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The reliability of three depression rating scales in a general population of Dutch older persons

Abstract: The CES-D was the most reliable scale for measuring depressive symptoms in a non-clinically depressed older population.

Cited by 20 publications

References 30 publications

Depression and Anxiety Following Deep Brain Stimulation in Parkinson’s Disease: Systematic Review and Meta-Analysis

Depression and Anxiety Following Deep Brain Stimulation in Parkinson’s Disease: Systematic Review and Meta-Analysis

Validation of the Amsterdam IADL Questionnaire©, a New Tool to Measure Instrumental Activities of Daily Living in Dementia

Genome-wide association study of depressive symptoms in the Hispanic Community Health Study/Study of Latinos

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