Abstract. The case histories and ECGs of 215 patients with a diagnosis of recent myocardial infarction have been examined with special reference to atypical findings. One hundred and seventy‐six had their first infarction, while 39 had had at least one myocardial infarction previously. Sixty‐eight per cent had typical and thirty‐two per cent atypical ECGs according to accepted criteria. The different non‐diagnostic ECG patterns are summarized, showing that 40% had ST‐T changes as the main change, 17% unchanged Q‐wave pattern from previously known myocardial infarctions, and 21% the R/S pattern of Perloff (19). It is suggested that patients with this R/S pattern (in the absence of pitfalls of Perloff) should be considered to have strictly posterior myocardial infarctions. The inclusion of these patients would increase the diagnostic score from 68% to 75% in the present study. No patient had a completely normal ECG. Discussion of some simple, general ECG principles shows that one can never expect to diagnose more than a certain number of recent myocardial infarctions in the ECG. The most common reasons for the ECG being non‐diagnostic of myocardial infarction are summarized. It is also stressed that Q‐wave patterns are not always diagnostic of myocardial infarctions, as they may also be seen in other, more rare forms of heart disease, probably most often in primary myocardial disease. Ten per cent had atypical case histories, and the different presenting symptoms are summarized. Thorough examination of patients with such symptoms with special reference to possible myocardial infarction as the underlying cause may disclose a certain number of recent myocardial infarctions which would otherwise have been overlooked.