The relevance of hierarchies, territories, defeat for depression in humans: hypotheses and clinical predictions

How does sex matter? Behavior, stress and animal models of neurobehavioral disorders

“…Loss events, including loss of rank and resources, are associated with higher risk of affective disorders (Brown, 1993;Siegrist and Marmot, 2004). Based on ethological concepts from animal research such as territorial aggression and hierarchy, loss of rank and resources seem to be crucial factors determining the physiological alterations associated with depressed mood and anxiety and even clinical signs of depression in men (Price et al, 1994;Nesse, 1999;Rohde, 2001;Sloman et al, 2003;Parmigiani et al, 2009). This is known as the "social competition hypothesis" that "predicts that depression is linked to hierarchical defeat in humans' (Rohde, 2001;p.…”

Psychological pathway to suicidal ideation among men who have sex with men in Shanghai, China: A structural equation model

“…A later empirical study (Kleiman et al, 2014) integrating HT and IPTS suggested that negative cognitive styles were distal factors, and perceived burdensomeness and thwarted belongingness proximal M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT ones for suicidal ideation. According to Rohde (2001), perceived burdensomeness and thwarted belongingness are conceptually similar to defeat and entrapment in their shared emphasis on the negative appraisal of social rank, but the latter relate more to internal expectancies and could be more generic.…”

Chronic social stress, hedonism and vulnerability to obesity: Lessons from Rodents

“…Such an increase of body weight in RS was observed as main result of the accumulation of the visceral fat pads since no alteration of food intake was in this study evidenced. It is hypothesized (Bartolomucci et al, 2001(Bartolomucci et al, , 2004Rohde, 2001) that, as consequence of the loss of the territory ownership, RS animals are more prone to develop a complex psychosocial stress syndrome which is characterized by deficits of the immunological function (i.e., thymus atrophy), fat deposition and body weight gain. Thus, the mutual interaction between the loss of territory resources and subordinate social status appear to generate a stress-related synergism capable to disrupt the metabolic balance with a possible alteration of energy expenditure.…”