The Relevance of Autophagy within Inner Ear in Baseline Conditions and Tinnitus-Related Syndromes
Gloria Lazzeri,
Francesca Biagioni,
Michela Ferrucci
et al.
Abstract:Tinnitus is the perception of noise in the absence of acoustic stimulation (phantom noise). In most patients suffering from chronic peripheral tinnitus, an alteration of outer hair cells (OHC) starting from the stereocilia (SC) occurs. This is common following ototoxic drugs, sound-induced ototoxicity, and acoustic degeneration. In all these conditions, altered coupling between the tectorial membrane (TM) and OHC SC is described. The present review analyzes the complex interactions involving OHC and TM. These … Show more
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