The relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles

Antiinflammatory, lack of central analgesia and antipyretic properties of Acanthus montanus (Ness) T. Anderson

“…This is because sedatives and myorelaxants interfere with the results to give false positives (Woolfe and MacDonald, 1944). The relaxant properties of this plant have been demonstrated by Adeyemi et al (1999) on an intestinal smooth muscle. To confirm the lack of central analgesic properties, tail immersion test results were completely insignificant.…”

Pharmacological Basis for the Medicinal Use of Psyllium Husk (Ispaghula) in Constipation and Diarrhea

“…In order to explore whether nitric oxide/cyclic guanosine monophosphate (NO-cGMP) pathways were involved in the antispasmodic effect of the test material, the tissues were pretreated with L-NAME (0.1 mM) or methylene blue (10 lM) 30 min before redetermining the effect of the test substance [40].…”

The analgesic effect of the methanolic extract of Acanthus montanus

“…We found no relevant literature substantiating the uses indicated. As part of our pharmacological screening of this plant, we previously demonstrated that the methanolic extract of Acanthus montanus produces relaxation of intestinal smooth muscles (Adeyemi et al, 1999). The purpose of the present study was, therefore, to evaluate the analgesic effect of the methanolic extract using several acute and chronic models of pain in mice and rats.…”