The relationships between glycemic index and glycemic load
of diets and nutritional status and antioxidant/oxidant status
in the serum of patients with lung cancer

Zabłocka‐Słowińska, Katarzyna; Skórska, Katarzyna; Płaczkowska, Sylwia; Prescha, Anna; Pawełczyk, Konrad; Kosacka, Monika; Porębska, Irena; Grajeta, Halina

doi:10.17219/acem/98952

Cited by 3 publications

(3 citation statements)

References 39 publications

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“…It has been widely demonstrated that healthy diets and physical activity have beneficial effects in several pathological conditions including cancer [55,56]. Several studies have highlighted how some foods with a high glycemic index or inflammatory index are associated with chronic inflammation, and in turn, to a plethora of inflammatory-related diseases including cancer, diabetes, and cardiovascular diseases [57,58]. Indeed, nutrients can directly or indirectly modulate the molecular and physiological mechanisms responsible for cell proliferation, differentiation, and programmed cell death.…”

Section: Discussionmentioning

confidence: 99%

Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity

Falzone

Grimaldi

Celentano

et al. 2020

Cancers

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Background: Several studies have shown that healthy lifestyles prevent the risk of breast cancer (BC) and are associated with better prognosis. It was hypothesized that lifestyle strategies induce microRNA (miRNA) modulation that, in turn, may lead to important epigenetic modifications. The identification of miRNAs associated with BC, diet, and physical activity may give further insights into the role played by lifestyle interventions and their efficacy for BC patients. To predict which miRNAs may be modulated by diet and physical activity in BC patients, the analyses of different miRNA expression datasets were performed. Methods: The GEO DataSets database was used to select miRNA expression datasets related to BC patients, dietary interventions, and physical exercise. Further bioinformatic approaches were used to establish the value of selected miRNAs in BC development and prognosis. Results: The analysis of datasets allowed the selection of modulated miRNAs associated with BC development, diet, and physical exercise. Seven miRNAs were also associated with the overall survival of BC patients. Conclusions: The identified miRNAs may play a role in the development of BC and may have a prognostic value in patients treated with integrative interventions including diet and physical activity. Validation of such modulated miRNAs on BC patients undergoing lifestyle strategies will be mandatory.

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Section: Discussionmentioning

confidence: 99%

Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity

Falzone

Grimaldi

Celentano

et al. 2020

Cancers

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“…Total oxidant status (TOS) was measured in serum using the earlier described method [ 20 ], in which the oxidants present in the sample oxidize the ferrous ion-o-dianisidine complex to ferric ion (o-dianisidine dihydrochloride, ref. No: D3235; ammonium iron (II) sulfate hexahydrate, ref.…”

Section: Methodsmentioning

confidence: 99%

Exploring the Relationship between Antioxidant Enzymes, Oxidative Stress Markers, and Clinical Profile in Relapsing–Remitting Multiple Sclerosis

Bizoń,

Chojdak-Łukasiewicz,

Budrewicz

et al. 2023

Antioxidants

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We aimed to investigate the extent of alterations in the pro/antioxidant balance in the blood of patients with relapsing–remitting multiple sclerosis (RRMS) in relation to drug-modified therapy, gender, disability score, and disease duration. 161 patients (67 men and 94 women, aged 24–69 years, median 43.0) and 29 healthy individuals (9 men and 20 women, aged 25–68 years, median 41.0) were included in the study. We measured the activity of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) as well as the concentration of interleukin-6 (IL-6), lipid peroxidation parameters (LPO), total oxidant status (TOS), and total antioxidant capacity (TAS). The activity of SOD did not show any significant differences between patients with RRMS and the control group in our study. In contrast, significant decreased GPx activity and increased CAT activity was observed in the blood of patients with RRMS compared to the control group. Additionally, the activity of CAT was influenced by gender and the use of disease-modifying therapies. Disease-modifying therapies also affected the concentration of TOS, TAS, and LPO. Our studies indicated that enhancing GPx activity may be more beneficial to providing potential therapeutic strategies aimed at modulating antioxidant defenses to mitigate oxidative stress in this disease.

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“…Mobile phase was composed of 0.2% trifluouroacetic acid in methanol. External standards of gallic acid, protocatechuic acid, 4‐hydroxybenzoic acid, syringic acid, p ‐coumaric acid, and ferulic acid were used for the identification and quantification (Zabłocka‐Słowińska et al., 2019).…”

Section: Methodsmentioning

confidence: 99%

Impact of fractionation on fatty acids composition, phenolic compounds, antioxidant characteristics of olein and super olein fractions of flaxseed oil

Azad

Nadeem

Gulzar

et al. 2021

J. Food Process. Preserv.

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Flaxseed oil was fractionated at −40°C, filtrate was designated as olein fraction (31% yield), which was further fractionated at −60°C, and filtrate was named as super olein fraction (17% yield). Flaxseed oil, olein, and super olein fractions were stored at 25°C–30°C for the duration of 90 days. Alpha linolenic acid in flaxseed oil, olein, and stearin fraction was 55.26%, 63.47%, and 71.61%. High‐performance liquid chromatography (HPLC) characterization showed that phenolic compound was concentrated in olein and super olein fractions. In super olein fraction of flaxseed oil, concentration of gallic acid, protocatechuic acid, 4‐hydroxybenzoic acid, syringic acid, p‐coumaric acid, and ferulic acid was 8.14, 40.59, 75.38, 7.95, and 9.27 mg/100 g. Total phenolic contents of flaxseed oil, olein, and super olein were 145, 185, and 247 mg GAE/100 g. Peroxide value of 90 days stored flaxseed oil, olein, and super olein was 0.59, 0.75, and 0.96 (MeqO2/kg) with no difference in color and flavor scores. Practical applications Several fractions of palm oil and milk fat are commercially produced for large number of industrial applications. However, fractionation of flaxseed oil is not previously performed, and chemical characteristics of olein and super olein fractions of flaxseed oil are not reported in literature. In this study, olein and super olein fractions of flaxseed oil were produced by dry fractionation. Super olein fraction revealed more than 70% alpha linolenic, higher magnitude of phenolic compounds than parent flaxseed oil, with reasonable oxidative stability and acceptable sensory attributes. Olein and super olein fraction of flaxseed oil may be conveniently used for the supplementation of large number of food products.

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The relationships between glycemic index and glycemic load of diets and nutritional status and antioxidant/oxidant status in the serum of patients with lung cancer

Cited by 3 publications

References 39 publications

Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity

Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity

Exploring the Relationship between Antioxidant Enzymes, Oxidative Stress Markers, and Clinical Profile in Relapsing–Remitting Multiple Sclerosis

Impact of fractionation on fatty acids composition, phenolic compounds, antioxidant characteristics of olein and super olein fractions of flaxseed oil

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