The relationship of the ‘inferior constrictor swallow’ and ‘globus hystericus’ or the hypopharyngeal syndrome

Gray, Linsay

doi:10.1017/s0022215100094688

Cited by 31 publications

(11 citation statements)

References 10 publications

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“…Paradoxically, this dry swallow habit has been postulated as an indirect cause of the symptom, perhaps by building up a column of air periodically trapped beneath the upper esophageal sphincter. 4 A dependable abnormality in upper esophageal sphincter function has not been detected. Overt gastroesophageal reflux disease is found in more than a quarter of patients presenting with globus-like symptoms.…”

Section: Physiologic Featuresmentioning

confidence: 98%

Functional Esophageal Disorders

et al. 2006

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Section: Physiologic Featuresmentioning

confidence: 98%

Functional Esophageal Disorders

et al. 2006

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“…Nevertheless, manometric studies in later years found no supporting evidence [3]. However, this is contradicted by study of Gray [4] where he stated that cricopharyngeal muscle sphincter pressures measured using manometry revealed statistically significant differences between those with globus and controls. Also, Khalil et al [5] felt that globus was related to excess laryngeal and pharyngeal tension.…”

Section: Introduction and Literature Reviewmentioning

confidence: 94%

Positive findings on barium swallow in patients presenting with a “sensation of a lump in the throat”

Mahrous

Kaoutzanis

Amin

et al. 2011

Eur Arch Otorhinolaryngol

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Our objective is to evaluate the pickup rate of a significant pathology, on barium swallow, in patients who present to our clinic with a feeling of a lump in the throat (globus symptoms). Hospital--secondary referral centre. This is a retrospective study of 192 patients who had barium swallow in our department between August 2009 and August 2010. We revised 500 case notes to rule in 192 who presented with only a feeling of a lump in their throat. All patients with positive clinical findings, such as dysphagia, odynophagia, referred otalgia, hoarseness of voice, weight loss, neck swelling or vocal cord palsy, were ruled out. Eight patients were diagnosed on barium swallow as having significant pathology: five with diverticulae and three patients with oesophageal web. The percentage of significant pathology in our study is 4.17% (eight patients). Out of those eight cases, there was no malignant pathology identified on further panendoscopy. Our conclusion is that barium swallow adds very little to the diagnosis of Globus Pharyngeus, but it plays a role in the reassurance particularly from the patients' perspective.

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“…The interprandial dry swallow frequency increases as subjects try to “dislodge” the foreign body. Paradoxically, this dry swallow habit has been postulated as an indirect cause of the symptom, perhaps by building up a column of air periodically trapped beneath the upper esophageal sphincter 4. A dependable abnormality in upper esophageal sphincter function has not been detected.…”

Section: A1 Globusmentioning

confidence: 99%

Functional esophageal disorders

Clouse

Richter

Heading

et al. 1999

Gut

111

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The functional esophageal disorders include globus, rumination syndrome, and symptoms that typify esophageal diseases (chest pain, heartburn, and dysphagia). Factors responsible for symptom production are poorly understood. The criteria for diagnosis rest not only on compatible symptoms but also on exclusion of structural and metabolic disorders that might mimic the functional disorders. Additionally, a functional diagnosis is precluded by the presence of a pathology-based motor disorder or pathological reflux, defined by evidence of reflux esophagitis or abnormal acid exposure time during ambulatory esophageal pH monitoring. Management is largely empirical, although eYcacy of psychopharmacological agents and psychological or behavioral approaches has been established for serveral of the functional esophageal disorders. As gastroesophageal reflux disease overlaps in presentation with most of these disorders and because symptoms are at least partially provoked by acid reflux events in many patients, antireflux therapy also plays an important role both in diagnosis and management. Further understanding of the fundamental mechanisms responsible for symptoms is a priority for future research eVorts, as is the consideration of treatment outcome in a broader sense than reduction in esophageal symptoms alone. Likewise, the value of inclusive rather than restrictive diagnostic criteria that encompass other gastrointestinal and non-gastrointestinal symptoms should be examined to improve the accuracy of symptom-based criteria and reduce the dependence on objective testing.

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The relationship of the ‘inferior constrictor swallow’ and ‘globus hystericus’ or the hypopharyngeal syndrome

Cited by 31 publications

References 10 publications

Functional Esophageal Disorders

Functional Esophageal Disorders

Positive findings on barium swallow in patients presenting with a “sensation of a lump in the throat”

Functional esophageal disorders

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