The Relationship of SRY Determining Region Y Box 2 (SOX2) Immunohistochemical Expression with Stromal and Intratumoral TILs (Tumor Infiltrating Lymphocytes) in Patients with Ovarian Serous Tumors
Abstract:Background: Ovarian serous tumors are the most common epithelial tumors in premenopausal and postmenopausal, 60% of the most common cases are ovarian cystadenoma, 25% of low grade and highgrade serous carcinoma. Tumor infiltrating lymphocytes (TILs) is used to predict the prognosis some solid tumors. SRY (sex determining region Y)-box 2 (SOX2) is a transcription factor. High SOX2 in ovarian tumors associated with reduced disease-free survival. Research Objective: To determine the relationship between SOX2 expr… Show more
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