The Relationship of Pruritus and Local Skin Conditions to the Development of Vitiligo

Levai, Marian

doi:10.1001/archderm.1958.01560090088018

Cited by 14 publications

(6 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Kaposi was the first to point out that the starting point of some vitiligo lesions could be caused by local conditions 18 . Several reports have subsequently shown that the Koebner phenomenon occurs in the majority of vitiligo patients 19–27 . In our experience, vitiligo vulgaris macules frequently appear at sites subjected to repeated mechanical traumas of various origins, e.g.…”

supporting

confidence: 56%

Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo

Gauthier¹,

Cario‐André²,

Lepreux³

et al. 2003

Br J Dermatol

160

106

View full text Add to dashboard Cite

Detachment and transepidermal elimination of melanocytes following minor mechanical trauma in non lesional vitiligo skin is probably the cause of depigmentation occurring in the isomorphic response (Koebner phenomenon). We propose that transepidermal elimination of melanocytes in vitiligo should be regarded as a possible mechanism of chronic loss of pigment cells, perhaps previously damaged by another process.

show abstract

supporting

confidence: 56%

Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo

Gauthier¹,

Cario‐André²,

Lepreux³

et al. 2003

Br J Dermatol

160

106

View full text Add to dashboard Cite

show abstract

“…Pruritus in vitiligo was first reported in 1958. 6 Published data on the prevalence and characteristics of itch in vitiligo are very limited. In a study of 245 patients with generalized vitiligo, 20% of patients had pruritus.…”

Section: Discussionmentioning

confidence: 99%

Prurigo nodularis in vitiligo patches: An unusual observation

Saleh

2020

JAAD Case Reports

View full text Add to dashboard Cite

“…The prevalence of itch in this study is higher than a previous report. According to a study by Levai, 44% of vitiligo patients had a history of prior skin disease in an area of depigmentation, 15% had depigmentation in areas of constant pressure or irritation, and 10% complained of itching without prior history of skin disease or trauma [ 8 ]. The higher prevalence of itch in our study could be due to the differences in the study population.…”

Section: Discussionmentioning

confidence: 99%

“…However, itch was occasionally mentioned in some vitiligo patients. According to a study by Levai, vitiligo affected patients, with or without the presence of irritated skin lesions, can suffer from itch prior to the appearance of depigmented patches [ 8 ]. Furthermore, published data on the prevalence and characteristics of itch in vitiligo are very limited.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Clinical Characteristics of Itch in Vitiligo and Its Clinical Significance

Vachiramon

Onprasert

Harnchoowong

et al. 2017

BioMed Research International

View full text Add to dashboard Cite

Objective Vitiligo usually presented as asymptomatic depigmented macules and patches. Little is known regarding itch in vitiligo. This study aimed to evaluate the prevalence and characteristics of itch in vitiligo patients. Patients and Methods A cross-sectional study was conducted on vitiligo patients. Itch character and intensity were determined through questionnaires. Evaluation was also made by dermatologists to define vitiligo subtype, body surface area, Koebner phenomenon (KP), and so on. Data were assessed by computer software. Results were considered statistically significant if p < 0.05. Results Among 402 patients, itch on vitiliginous lesion presented in 20.2%. Prevalence of itch was most common in focal vitiligo (29.4%), followed by segmental vitiligo (20.3%) and nonsegmental vitiligo (19.6%), respectively. Tingling sensation was the most common itch-related symptom (82.7%). The median itch intensity is 5 by 10-point visual analog scale. Daily activity and sleep disturbance were observed in 60.5% and 39.5% of patients who experience itch. Itch occurred approximately 3 days prior to the development of lesions in 48.1% of patients. Thirty-two patients (78.1%) with both itch and KP type IIb had active disease. Conclusions Itch in vitiligo is not uncommon. The presence of itch with KP type IIb may warrant the active vitiligo.

show abstract

The Relationship of Pruritus and Local Skin Conditions to the Development of Vitiligo

Cited by 14 publications

References 4 publications

Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo

Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo

Prurigo nodularis in vitiligo patches: An unusual observation

Prevalence and Clinical Characteristics of Itch in Vitiligo and Its Clinical Significance

Contact Info

Product

Resources

About