The relationship of physical activity to bone mineral content in postmenopausal women

Gauthier, Pierre; Laflamme, Lucie; Deshaies, Paul; Picard, D

doi:10.1016/s0167-4943(05)80017-2

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…Thus, external loaded stimulations affect bone as theorized by Wolff's law, and it is expected that the stimulation of exercise reduces the degree of bone loss. Walking and weight-bearing exercises of aged people or postmenopausal women have demonstrated the prevention of bone reduction [12][13][14] . Also some experiments of treadmill running have been reported 15,16) .…”

Section: Discussionmentioning

confidence: 99%

Effect of the Physical Activity on Bone in Ovariectomized Mice.

et al. 2000

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Abstract. The effects of physical activity, treadmill running, on bone of ovariectomized mice were investigated. Forty 12-week-old female ICR mice were used. They were ovariectomized (OVX) or shamoperated (SHAM) and half of them were run on a treadmill at 16 m/min, 5 days/week for 6 weeks (Ex). All animals were sacrificed at week 12 after operation. Mechanical strength of the left femur and tibia were measured by the three-point bending strength test. The bones were dried, weighed and burned to ash. Mechanical strength and ash content of the femur and tibia in Ex group were significantly higher than those of control animals. Also mechanical strength of femur and tibia in OVX/Ex were not different from SHAM/Cont mice. Physical activity, treadmill running, thus affected inhibition of bone loss and maintenance of bone mass. It is necessary to continue this basic study to determine effective modes of physical activity.

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Section: Discussionmentioning

confidence: 99%

Effect of the Physical Activity on Bone in Ovariectomized Mice.

et al. 2000

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Therapy of Osteoporosis: Calcium, Vitamin D, and Exercise

Reid

1996

The American Journal of the Medical Sciences

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Therapy of Osteoporosis: Calcium, Vitamin D, and Exercise

Reid¹

1996

The American Journal of the Medical Sciences

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Calcium supplementation has long been regarded as a fundamental part of the prevention and treatment of postmenopausal osteoporosis, but it is only in recent years that clear evidence has emerged demonstrating its impact on bone mass. Calcium supplementation does not completely arrest postmenopausal bone loss but slows the rate of decline by 30 to 50%. The effect of calcium supplementation on fracture incidence in postmenopausal women has not been established. Vitamin D deficiency is common in the frail elderly, particularly in countries where fortification or food with this vitamin is not practiced. Treatment of vitamin D deficiency has been associated with significant reductions in the number of hip fractures. The role of the potent vitamin D metabolites, calcitriol and alphacalcidol, in the management of postmenopausal osteoporosis is not clear. Although some studies show substantial benefits in bone density or fracture rate from the use of these compounds, the published data are inconsistent. In general, hormone replacement therapy and the potent bisphosphonates produce greater effects on bone density and there is a greater consistency among the results of the published studies of these other interventions. Controlled trials of exercise interventions in postmenopausal women show that exercise can positively influence bone density by a few percent. Exercise interventions in the elderly have been reported to decrease fall frequency by 10%. This latter effect may have a greater impact on fracture frequency than the modest benefits of exercise on bone-density.

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The relationship of physical activity to bone mineral content in postmenopausal women

Cited by 3 publications

References 16 publications

Effect of the Physical Activity on Bone in Ovariectomized Mice.

Effect of the Physical Activity on Bone in Ovariectomized Mice.

Therapy of Osteoporosis: Calcium, Vitamin D, and Exercise

Therapy of Osteoporosis: Calcium, Vitamin D, and Exercise

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