The relationship of GH and LEP gene polymorphisms with fat-tail measurements (fat-tail dimensions) in fat-tailed Makooei breed of Iranian sheep

Hajihosseinlo, Abbas; Jafari, Sanaz; Ajdary, Marziyeh

doi:10.4103/2277-9175.163995

Cited by 8 publications

(1 citation statement)

References 16 publications

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“…The growth hormone (GH) gene plays an important role in postpartum growth, milk production, tissue growth, and reproduction, such as metabolism of proteins, carbohydrates, and fats [2,3]. Growth hormone gene in sheep is about 1.8 kilobytes long and contains five exons and four introns [4,5]. Mentioned that growth hormone is a anabolic hormone that is synthesized and secreted by the somatic cells of the anterior pituitary gland in a daily and pulsating manner.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Growth Hormone Genetic Polymorphism in Awassi Ewes and Their Newborns Using PCR-RFLP Technology

Hady,

Almallah,

Al-Hasan

2024

Egyptian Journal of Veterinary Sciences

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Production to determine the genetic structures (Genotype) of the Growth hormone gene for Awassi ewes and their progeny and compares between them, For conducting this work, forty Awassi ewes of age (3-5) years and 20 lambs aged between birth and weaning (1-3) months were used, The DNA was separated from collected blood samples, growth hormone gene was amplified using specific primers and genotyping was performed using RFLP technique. The distribution ratios of the genetic structures varied in the ewes, as only two genetic structures appeared, namely AA and AG, with a frequency of 0.24 for the AA and 0.16 for the AG genetic structure, and with a allele frequency of (0.8) for the A allele and (0.2) for the G allele, while three genotypes appeared for the lambs, namely AA, AG and GG, with the distribution ratios of the genetic structures (0.75, 0.1 and 0.15) respectively and with the same allelic frequency (0.8, 0.2) for each of the allele (A and G) respected . We conclude from this study that it is possible to consider the multiple genetic form of the growth hormone gene and its dependence on genetic improvement in ewes and their newborns to achieve a higher economic return than selection methods.

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Section: Introductionmentioning

confidence: 99%

Comparison of Growth Hormone Genetic Polymorphism in Awassi Ewes and Their Newborns Using PCR-RFLP Technology

Hady,

Almallah,

Al-Hasan

2024

Egyptian Journal of Veterinary Sciences

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Sheep Genetic Diversity and Breed Differences for Climate-Change Adaptation

Elbeltagy¹

2017

Sheep Production Adapting to Climate Change

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Influence of DNA-Markers Kap 1.3, Cast, Lep 387 on the Productivity of Sheep of the Caucasian and Edilbaevskaya Breeds

LUSHNIKOV

Strilchuk

2022

BIO Web Conf.

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Recently, all over the world, breeding work has been carried out with the active use of the methods of modern genetics. The article presents the results of a study of the relationship between the DNA markers of calpastatin (CAST) and leptin (LEP 387) with the meat productivity of Edilbaev sheep, as well as KAP 1.3 with the wool productivity of Caucasian sheep. It was revealed that these DNA markers have a sufficient level of polymorphism in the studied breeds, as well as presence of a relationship between the genotypes of the studied DNA markers with the productivity of the studied breeds.

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The relationship of GH and LEP gene polymorphisms with fat-tail measurements (fat-tail dimensions) in fat-tailed Makooei breed of Iranian sheep

Cited by 8 publications

References 16 publications

Comparison of Growth Hormone Genetic Polymorphism in Awassi Ewes and Their Newborns Using PCR-RFLP Technology

Comparison of Growth Hormone Genetic Polymorphism in Awassi Ewes and Their Newborns Using PCR-RFLP Technology

Sheep Genetic Diversity and Breed Differences for Climate-Change Adaptation

Influence of DNA-Markers Kap 1.3, Cast, Lep 387 on the Productivity of Sheep of the Caucasian and Edilbaevskaya Breeds

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