“…In general, mixed results have been found. Schuler ( 1930), Malzberg (1940), Patterson & Zeigler (1941), Sherman & Kraines (1943), , Alanen (19581, and Schooler (1961), have reported minimal, although generally positive effects. In the Patterson & Zeigler study, for example, a sample of 442 male and female schizophrenics, who had been studied over a long period of time at the Neuropsychiatric Institute of the University Hospital, Ann Arbor, Michigan, were compared with 495 controls from the general medical services of the same hospital.…”