The relationship of asymmetric dimethylarginine levels with uncontrolled arterial hypertension and hypertension disease stage
Aleksandr N. Stafeev,
Nadezhda I. Logvinenko,
Sergey V. Astrakov
Abstract:Background: Patients with treatment-resistant hypertension have a worse cardiovascular prognosis compared to those who achieve their target levels of blood pressure (BP). One of biochemical and clinical markers of a decreased response to antihypertensive therapy can be asymmetric dimethylarginine (ADMA), a molecule that reduces formation of nitric oxide and promotes endothelial dysfunction and vasoconstriction.
Aim: To assess the status of the nitrogen oxide synthesis system and clinical and laboratory p… Show more
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