The Relationship Between Tonsillar Size and Neutrophil-to-Lymphocyte Ratio in Children With Recurrent Tonsillitis

Abstract

To explore the relationships between tonsillar sizes and neutrophil-to-lymphocyte ratio (NLR) values in children with recurrent tonsillitis. Subjects and Methods: In total, 236 children (128 males, 108 females; average age 11.80±9.16 years; range, 4-18 years) who underwent tonsillectomy with a diagnosis of recurrent tonsillitis were included. The patients were divided into four groups according to the tonsillar sizes. Group A was consist of 56 children with grade 1 tonsil size, while group B, C and D was consist of 58, 70 and 52 children with grade 2, 3 and 4 tonsil size, respectively. Pre-operative NLR values of all groups were compared with measurements in the post-operative third month. Results: In group A, pre-operative NLR levels were 1.76±0.92, while post-operative NLR were 1.74±1.53. No statistically significant difference in NLR values was observed between pre-and post-operatively in group A (p=0.864). In group B, pre-operative NLR levels were 1.56±1.14, while post-operative NLR were 1.29±0.65. In group C, pre-operative NLR levels were 1.48±1.47, while post-operative NLR were 1.22±0.79. In group D, pre-operative NLR levels were 1.44±1.52, while post-operative NLR were 1.19±0.96. Post-operative NLR values were significantly lower than pre-operative NLR values in both groups B, C, D (p=0. 012, p=0.036, p=0.043, respectively). Conclusion: The larger tonsils affect the NLR levels and larger tonsils are strongly suspected to contribute to higher systemic inflammations. However, higher systemic inflammations can be prevented by tonsillectomy.

Adenoidektomi, Tonsillektomi ve Adenotonsillektomi Planlanan Pediatrik Hastalarda Ortalama Trombosit Hacmi, Nötrofil/Lenfosit Oranı, Trombosit/Lenfosit Oranı ve Erken Postoperatif Anestezi Komplikasyonları

“…[26,27] Diğer taraftan çocuklarda tonsil boyutu ile NLO düzeyi arasında pozitif bir ilişki olduğu bildirilmiştir. [28] Nötrofil/lenfosit oranı Yorulmaz ve ark., [29] tarafından yapılan bir çalışmada 1,48'in üzerindeki NLO değerinin tonsillektomi için endikasyon nedeni olmamakla birlikte endikasyonu güçlendirebilecek bir parametre olduğu bildirilmiştir. Baran ve ark., [9] tarafından yapılan bir çalışmada da NLO parametresinin tonsillit hastalarında inflamatuvar bir belirteç olarak kullanılabileceği öne sürülmüştür.…”

Features of the Course of Tonsillitis in Children Infected With the Herpes Virus

“…Beta-hemolytic group A streptococci are most often isolated from the surface of the tonsilsup to 30% [6,7]. Many authors consider streptococcal tonsillitis in childhood as a trigger for certain somatic diseases, such as glomerulonephritis, rheumatoid arthritis, rheumatism, and others.…”