2022
DOI: 10.53730/ijhs.v6ns7.13617
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The relationship between tissue inhibitor metalloproteinase-1 with colorectal cancer and tissue inhibitor metalloproteinase-1 as a predictor of colorectal cancer

Abstract: Colorectal cancer is reported as the third most common case worldwide in men and accounts for 10% of all cancers. Matrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases that affect the degradation and remodeling of extracellular components and contribute to the three Hallmarks of cancer. TIMP-1 is an endogenous MMP inhibitor with multiple functions related to the tumor microenvironment and colorectal cancer development. This study used a prospective cohort study design to prove tha… Show more

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