The relationship between symptom severity, stigma, illness intrusiveness and depression in Mal de Debarquement Syndrome

Abstract

Mal de Debarquement Syndrome is a neurological disorder of motion perception, triggered by external motion. This study aimed to determine the importance of psychosocial factors in relation to depression and quality of life in Mal de Debarquement Syndrome. A total of 66 participants with self-reported Mal de Debarquement Syndrome completed quality-of-life, symptom severity, stigma, depression, and illness intrusiveness measurements in this naturalistic correlational study. Mal de Debarquement Syndrome was associated with high levels of depression and illness intrusiveness. Illness intrusiveness mediated between stigma and quality of life; also the level of stigma moderated the effect of illness intrusiveness on quality of life. Targeted interventions aimed at alleviating psychological distress may improve quality of life in Mal de Debarquement Syndrome.

Double-Blind Sham-Controlled Crossover Trial of Repetitive Transcranial Magnetic Stimulation for Mal de Debarquement Syndrome

“…Moreover, migraine and other headache types can develop in MdDS along with visual motion intolerance, fatigue and cognitive slowing (16, 17). Though medications like benzodiazepines and selective serotonin reuptake inhibitors (SSRI) can provide some symptom relief, they provide palliation rather than induce remission.…”

“…Though medications like benzodiazepines and selective serotonin reuptake inhibitors (SSRI) can provide some symptom relief, they provide palliation rather than induce remission. Because of limited accessible treatment options, patients with MdDS experience high social burden, low quality of life, and high rates of depression (17, 18). Therefore, experimental neuromodulation offers a positive benefit-to-risk ratio from a treatment standpoint with a rationale supported by central metabolic, brain volume, and functional connectivity differences in MdDS compared to healthy controls (19-23).…”

Mal de Debarquement Syndrome

“…These avoidance measures could raise the risk of developing a secondary mood disorder as social stigma and feelings of inefficacy increase, and general quality of life declines. 21,22 It is important to address these secondary symptoms as contributors to the overall morbidity of MdDS.…”

Mal de Debarquement sindromas: klinikiniai atvejai ir literatūros apžvalga

“…Þi noma, kad krui zi niai lai vai ápras tai siû buo ja ið vie nos pu sës á ki tà maþ daug 0,2 Hz, o tai su ke lia jû ros li gà [2]. Kai kuriems as me nims MdDS simp to mai pa si reið kë po ap si lanky mo at rak cio nø par ke, veiks mo þai di mø per "Nin ten -do®Wii" vaiz do þai di mø kon so le [14]. Simp to mai ga li pra si dë ti ið kart po ið li pi mo ið trans por to prie mo nës ar ba po 1 ar 2 die nø [11].…”

“…Sie kiant tai pa tvirtin ti, rei kia dau giau ty ri mø, lei dþian èiø vi sið kai su pras ti tiks lø me cha niz mà ðio trum pa lai kio simp to mø pa ge rë ji mo pa kar to ti nio pa sy vaus ju de sio sà ly go mis. Ta èiau il gos kelio nës, pa vyz dþiui, il gos truk mës skry dis, ga li pa sun kin ti simp to mus [14].…”