The Relationship Between Skeletal Muscle Serum Markers and Primary THA: A Pilot Study

Cohen, Russell G.; Katz, Jay A.; Skrepnik, Nebojša

doi:10.1007/s11999-009-0809-7

Cited by 31 publications

(15 citation statements)

References 34 publications

(55 reference statements)

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“…It has been argued that biomarkers may help to evaluate minimally invasive techniques against more traditional surgical approaches (Cohen et al, 2009 ;Hartzband et al, 2004) or against varying minimal trauma approaches under development. Chimento and coworkers (2005) compared their minimally invasive total hip arthroplasty procedure to the standard posterolateral approach.…”

Section: Relative Tissue Disruptionmentioning

confidence: 99%

Biochemical Measurement of Injury and Inflammation in Musculoskeletal Surgeries

Kumbhare¹,

Parkinson²,

Dunlop³

et al. 2012

Orthopedic Surgery

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Section: Relative Tissue Disruptionmentioning

confidence: 99%

Biochemical Measurement of Injury and Inflammation in Musculoskeletal Surgeries

Kumbhare¹,

Parkinson²,

Dunlop³

et al. 2012

Orthopedic Surgery

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“…Also, CK and myoglobin were found to rise after subcostal abdominal approaches and THA with myoglobin peaking on postoperative day 1 [16]. Additionally, serum markers of inflammation and muscle damage have been proposed as a potential measure of muscle damage in both total hip and total knee surgery [3,4,6,12].…”

Section: Introductionmentioning

confidence: 99%

“…One report noted that less damage occurred in the gluteus minimus muscles and minimus tendon with the direct anterior approach when compared with the posterolateral approach [22]. Another study evaluated serum markers of muscle damage in patients undergoing one of three different approaches to the hip (Watson Jones, miniposterior, and two-incision) and found no difference in trends of serum enzymes [6]. Most recently, however, serum markers of muscle damage and inflammation were reported to be much lower in patients undergoing a direct anterior approach as compared with a posterior approach [3].…”

Section: Introductionmentioning

confidence: 99%

No Correlation Between Serum Markers and Early Functional Outcome After Contemporary THA

Poehling-Monaghan

Taunton

Kamath

et al. 2017

Clinical Orthopaedics &Amp; Related Research

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Background Serum markers of inflammation and muscle damage have shown clinical utility in some areas of medicine, but their value in determining the invasiveness or in predicting the early functional outcomes after total hip arthroplasty (THA) has not been demonstrated.Questions/purposes (1) Do serum markers of inflammation/muscle damage predict pain or early functional outcomes after contemporary THA performed through a direct anterior or miniposterior approach? (2) Do early functional outcomes as measured by in-hospital outcomes and clinical milestones differ between a contemporary direct anterior and miniposterior approach for THA? Methods Between August 31, 2013, and September 1, 2014, all patients presenting as candidates for THA at our institution who had not already had preoperative blood draws (161) were recruited for this study. Forty-two patients failed these exclusion criteria, eight patients declined enrollment, and 11 were consented but did not complete the required preoperative blood tests. Recruitment stopped when 50 patients had been enrolled in both the direct anterior group and the miniposterior group (2n = 100) based on a priori power analysis. One high-volume surgeon performed all of the direct anterior approaches and three high-volume surgeons performed the miniposterior approaches. Groups did not differ with the numbers available in mean age (63 years; SD 10; range, 35-86 years), sex (52% female), or mean body mass index (mean 31 kg/m 2 ; SD 7 kg/m 2 ; range, 20-73 kg/m 2 ). Serum markers measured including hemoglobin, hematocrit, myoglobin, creatine kinase (CK), C-reactive protein, interleukin-6, and tumor necrosis factor-a were collected at the preoperative clinic visit and on postoperative days 1 and 2 and compared with operative details, in-hospital complications, therapy progress, pain scores, and One of the authors (MWP) or a member of his immediate family, has or may receive payments or benefits, during the study period, an amount of USD 100,001 to USD 1,000,000 from Stryker Orthopedics (Mahwah, NJ, USA). One of the authors (RTT) or a member of his immediate family, has or may receive payments or benefits, during the study period, an amount of USD 10,000 to USD 100,000 from DePuy Orthopedics (Warsaw, IN, USA). One of the authors (RJS) or a member of his immediate family, has or may receive payments or benefits, during the study period, an amount of USD 10,000 to USD 100,000 from ZimmerBiomet (Warsaw, IN, USA) and USD 10,000 to USD 100,000 from Link Orthopaedics (Rockaway, NJ, USA). One of the authors (MJT) or a member of his immediate family has or may receive payments or benefits, during the study period, less than USD 10,000 from DJO Orthopedics (Vista, CA, USA). One of the authors (AFK) or a member of his immediate family, has or may receive payments or benefits, during the study period, an amount of less than USD 10,000 from Innomed (Savannah, GA, USA) and has or may receive payments or benefits, during the study period, an amount of less than USD 10,000 from ZimmerBiomet...

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“…Recently, some researchers have used muscle damage markers to compare different approaches in orthopedic surgery. [15][16][17] The feasibility and effectiveness of this new approach have been proven. 16 The current study prospectively compared the medial parapatellar approach with the mini-midvastus approach in unilateral TKA according to muscle damage and inflammation markers and clinical and radiological results.…”

mentioning

confidence: 99%

Mini-midvastus Versus Medial Parapatellar Approach in TKA: Muscle Damage and Inflammation Markers

Huang¹,

Shen²,

Ma³

et al. 2012

Orthopedics

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The purpose of this prospective study was to analyze the biochemical markers of muscle damage and inflammation in patients treated with the mini-midvastus approach or the medial parapatellar approach for total knee arthroplasty. Of 60 patients who underwent unilateral total knee arthroplasty, 30 were treated with the mini-midvastus approach (MMV group) and 30 were treated with the medial parapatellar approach (MPP group). Serum creatine kinase, myoglobin, lactate dehydrogenase, glutamic oxaloacetic transaminase, C-reactive protein, interleukin-6, and interleukin-1β levels were measured preoperatively, immediately postoperatively (except for C-reactive protein level), and on postoperative days 1, 2, and 3. Student's t test, Pearson's chi-square test, and Fisher's exact test were used to compare the outcomes between the 2 groups. Compared with the MPP group, a significant increase in serum creatine kinase level existed in the MMV group on postoperative days 2 (P=.08) and 3 (P=.09) and cumulatively (P=.02). However, significantly elevated C-reactive protein and interleukin-6 levels existed in the MPP group.According to the serum creatine kinase levels, the mini-midvastus approach has no superiority over the medial parapatellar approach in terms of sparing muscle and may cause more muscle damage. Further study is warranted to determine the correlation between biochemical markers and functional deficits.

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The Relationship Between Skeletal Muscle Serum Markers and Primary THA: A Pilot Study

Cited by 31 publications

References 34 publications

Biochemical Measurement of Injury and Inflammation in Musculoskeletal Surgeries

Biochemical Measurement of Injury and Inflammation in Musculoskeletal Surgeries

No Correlation Between Serum Markers and Early Functional Outcome After Contemporary THA

Mini-midvastus Versus Medial Parapatellar Approach in TKA: Muscle Damage and Inflammation Markers

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