The relationship between serum lactate and VO2/VCO2 in patients undergoing coronary artery bypass grafting in Ardabil city hospital, 2017

Abstract

<p class="abstract"><strong>Background:</strong> VO<sub>2</sub>/VCO<sub>2</sub> ratio and blood lactate are different indices of adequacy of oxygen delivery to oxygen needs. The aim of this study was to investigate the relationship between serum lactate and VO<sub>2</sub>/VCO<sub>2</sub> in patients undergoing CABG in Ardabil city.</p><p class="abstract"><strong>Methods:</strong> This descriptive-analytical study was performed on 30 patients who underwent CABG at Ardabil city hospital during 2017. Demographic data of patients including age and sex were collected. Standard monitoring included electrocardiogram, invasive arterial pressure, pulse oximetry, end tidal carbon dioxide, temperature and urine output was done. The CAB was carried out through a CPB pump at the time of grafting. Blood lactate and VO<sub>2</sub>/VCO<sub>2</sub> were measured in 3 groups of patients based on number of grafts, EF and serum Creatinine. Collected data analyzed by statistical methods in SPSS version 19. </p><p class="abstract"><strong>Results:</strong> Most of patients were male (86.7%). The mean age of patients was 58.1 years. The blood lactate and VO<sub>2</sub>/VCO<sub>2</sub> values increased after surgery. There was no statistically significant difference in two groups based on number of grafts and serum Cr but it was statistically significant based on E/F. There was a significant correlation between Blood lactate and VO<sub>2</sub>/VCO<sub>2</sub> ratio in patients.</p><p class="abstract"><strong>Conclusions:</strong> The results showed that blood lactate as an indicator for patients status during CABG surgery can be replaced with VO<sub>2</sub>/VCO<sub>2</sub>.</p>