The relationship between serum 25‐hydroxy vitamin D, parathormone and bone mineral density in Indian population

Abstract

Less than half of the subjects with VDD have SHPT. BMD levels start to decline at PTH values currently considered to be normal. These data suggest the need to redefine SHPT in different age groups keeping in mind the relationship between PTH and BMD. This may also influence the decision to supplement subjects with VDD.

The Association Between Body Composition, 25(OH)D, and PTH and Bone Mineral Density in Black African and Asian Indian Population Groups

“…Within the current study, the BMD at all skeletal sites, except for the lumbar spine, correlated negatively with PTH in the AI subjects, whereas in the BA group, PTH correlated negatively with hip BMD only. Previous studies performed in AI subjects have yielded similar results to ours, with 25(OH)D demonstrating no correlation to BMD but PTH showing an inverse association with BMD (30,55). Adult African Americans are reported to show skeletal resistance to PTH (56), which may explain the lower incidence of osteoporotic fractures in black subjects.…”

“…All bone data were compared after adjustment for height, weight, age, and bone area. Pearsons correlations were used to examine the strength of the association of BMD with variables that have been shown to affect BMD (16,(27)(28)(29)(30)(31)(32). Multivariable regression analyses were performed to determine the variables that made a significant contribution to subtotal, lumbar, femoral, and hip BMD in the two ethnic groups.…”

Secondary surgery after sleeve gastrectomy: Roux-en-Y gastric bypass or biliopancreatic diversion with duodenal switch

“…A decrease in fat-soluble vitamins has also been described by Marceau et al [35] in a cohort of 1423 BPD/DS patients. This decrease in serum levels may lead to more deficiencyrelated complications, for example, night blindness [36] from vitamin A deficiency, and elevations in PTH and accelerated bone loss from vitamin D and calcium deficiency [37].…”

Prevalencia de insuficiencia y deficiencia de vitamina D en adultos mayores con fractura de cadera en Chile

“…Pacientes con niveles bajo 20 o 10 ng/dl tienen alto riesgo de sufrir hiperparatiroidismo secundario y disminución acelerada de la masa ósea, lo que ha sido demostrado en algunos estudios con densitometría ósea [24][25][26] . Estos pacientes presentan riesgo aumentado de sufrir fracturas por insuficiencia.…”