The Relationship Between Retruded Contact Position and Intercuspal Position in Patients with TMJ Osteoarthritis

Yamada, Kazuhiro; Fukui, Tadao; Tsuruta, Akemi; Hanada, Kooji; Hosogai, Akiko; Kohno, Shoji; Hayashi, Takafumi

doi:10.1080/08869634.2003.11746257

Cited by 6 publications

(10 citation statements)

References 13 publications

(3 reference statements)

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“…Dental malocclusion can cause OA in temporomandibular joint (TMJ). (16,17) In rodents, anterior cross-bite (UAC) imposed by dental prosthetics produces OA lesions in their TMJ cartilage as indicated by accelerated chondrocyte terminal differentiation and degradation of extracellular matrix. (18)(19)(20) Herein, we first investigated the impact of biomechanical stresses on CaSR expression and terminal cell differentiation by studying the effect of fluid flow shear stress (FFSS) on isolated TMJ chondrocytes and chondrogenic ATDC5 cells.…”

Section: Introductionmentioning

confidence: 99%

Prevention of Injury-Induced Osteoarthritis in Rodent Temporomandibular Joint by Targeting Chondrocyte CaSR

Zhang

Yang

Wan

et al. 2018

Journal of Bone and Mineral Research

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Traumatic joint injuries produce osteoarthritic cartilage manifesting accelerated chondrocyte terminal differentiation and matrix degradation via unknown cellular and molecular mechanisms. Here we report the ability of biomechanical stress to increase expression of the calcium‐sensing receptor (CaSR), a pivotal driver of chondrocyte terminal differentiation, in cultured chondrogenic cells subjected to fluid flow shear stress (FFSS) and in chondrocytes of rodent temporomandibular joint (TMJ) cartilage subjected to unilateral anterior cross‐bite (UAC). In cultured ATDC5 cells or TMJ chondrocytes, FFSS induced Ca2+ loading and CaSR localization in endoplasmic reticulum (ER), casually accelerating cell differentiation that could be abrogated by emptying ER Ca2+ stores or CaSR knockdown. Likewise, acute chondrocyte‐specific Casr knockout (KO) prevented the UAC‐induced acceleration of chondrocyte terminal differentiation and matrix degradation in TMJ cartilage in mice. More importantly, local injections of CaSR antagonist, NPS2143, replicated the effects of Casr KO in preventing the development of osteoarthritic phenotypes in TMJ cartilage of the UAC‐treated rats. Our study revealed a novel pathological action of CaSR in development of osteoarthritic cartilage due to aberrant mechanical stimuli and supports a therapeutic potential of calcilytics in preventing osteoarthritis in temporomandibular joints by targeting the CaSR. © 2018 American Society for Bone and Mineral Research.

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Section: Introductionmentioning

confidence: 99%

Prevention of Injury-Induced Osteoarthritis in Rodent Temporomandibular Joint by Targeting Chondrocyte CaSR

Zhang

Yang

Wan

et al. 2018

Journal of Bone and Mineral Research

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“…Of the 67 excluded publications (18, 32–97) that had evaluated the diagnostic efficacy of CT and MRI on TMJD but not at the diagnostic thinking and therapeutic level, the majority evaluated diagnostic accuracy efficacy ( n = 62) and were MRI studies ( n = 54) in which the results were described in terms of accuracy, yielding abnormal or normal diagnoses in case series, or evaluating the sensitivity and specificity of the diagnostic methods, and observer performance expressed as overall agreement, kappa index, or correlation coefficients (Table 4).…”

Section: Resultsmentioning

confidence: 99%

“…From all publications selected ( n = 257) for full‐text reading, only 47 used diagnostic criteria to establish the clinical diagnoses of the patient samples (16, 18, 42–44, 59, 63, 66, 67, 71, 78, 79, 81–83, 88, 89, 91, 93, 98–124). Of these 47 studies, 17 (18, 79, 81–83, 88, 89, 91, 98–104) used RDC/TMD (2), 11 (42, 59, 66, 105–111, 124) listed the criteria but did not refer to any validated criteria or TMD study, 14 (16, 43, 44, 63, 71, 93, 111–118) used criteria from other published TMD studies, and six (67, 68, 119–122) used the Helkimo Index (125). Among the efficacy studies (Table 4), 17 used diagnostic criteria (18, 42–44, 59, 63, 66–68, 71, 79, 81–83, 88, 89, 91), eight (18, 79, 81–83, 88, 89, 91) RDC/TMD (2), three (42, 59, 66) listed the criteria in the publication but did not refer to any validated criteria or TMD published study, four (43, 44, 63, 71) used criteria from previously published TMD studies, and two (67, 68) used the Helkimo Index (125).…”

Section: Resultsmentioning

confidence: 99%

“…Of these 47 studies, 17 (18, 79, 81–83, 88, 89, 91, 98–104) used RDC/TMD (2), 11 (42, 59, 66, 105–111, 124) listed the criteria but did not refer to any validated criteria or TMD study, 14 (16, 43, 44, 63, 71, 93, 111–118) used criteria from other published TMD studies, and six (67, 68, 119–122) used the Helkimo Index (125). Among the efficacy studies (Table 4), 17 used diagnostic criteria (18, 42–44, 59, 63, 66–68, 71, 79, 81–83, 88, 89, 91), eight (18, 79, 81–83, 88, 89, 91) RDC/TMD (2), three (42, 59, 66) listed the criteria in the publication but did not refer to any validated criteria or TMD published study, four (43, 44, 63, 71) used criteria from previously published TMD studies, and two (67, 68) used the Helkimo Index (125). After RDC/TMD (2), the Helkimo Index (125) was the most frequently used diagnostic criterion in the publications retrieved and selected for this systematic review.…”

Section: Resultsmentioning

confidence: 99%

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Do computed tomography and magnetic resonance imaging add to temporomandibular joint disorder treatment? A systematic review of diagnostic efficacy

Ribeiro-Rotta

Marques

Pacheco

et al. 2010

J of Oral Rehabilitation

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A question frequently asked in the clinical practice of the professional who treats temporomandibular joint disorders (TMJD) is 'To make the cost/benefit ratio worthwhile for the patient, when should I request a temporomandibular joint (TMJ) computed tomography (CT) or magnetic resonance imaging (MRI)?' To evaluate the evidence of the efficacy of CT and MRI in the diagnosis of disc displacement, local inflammatory disorders, and arthrosis of the TMJ at therapeutic efficacy level, PubMed and Cochrane literature searches with specific indexing terms and a hand search were made. From the retrieved titles and abstracts, three examiners selected publications on the basis of predetermined inclusion and exclusion criteria. Data were extracted from the selected publications using a previously established protocol. Publications considered relevant were interpreted with the aid of the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool and publications that critically evaluate systematic reviews. The literature search yielded 584 titles and abstracts, of which 257 were selected and read in full text. One study was judged relevant. This study evaluated evidence of the efficacy of MRI in the diagnosis of disc position and configuration, disc perforation, joint effusion, and osseous and bone marrow changes in the temporomandibular joint, but no publication reported diagnostic thinking efficacy or therapeutic efficacy. In conclusion, the absence of studies on the therapeutic efficacy of MRI and CT on TMJD reinforces the need for investment in decision-making studies; meanwhile, sectional imaging tests should be prescribed with caution, especially when health budgets are limited.

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“…When the mandible moves backwards from the ICP to that location, over approximately 1.5 mm [1] or 2.0 mm [7], the condylar position can be assessed as unstable, because the distance is long enough for a wide space behind the condyle at the ICP [25], [26], [27], [28]. The unstable condyle may exist unilaterally or bilaterally.…”

Section: Bone Change and Unstable Position Of The Condylementioning

confidence: 99%

A controversy with respect to occlusion

Fukushima

2016

Japanese Dental Science Review

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SummaryThere are very little controversies on occlusion in healthy individuals, where centric relation is regarded as the criterion for assessing the present occlusion and also for establishing a new occlusal relationship between the upper and the lower jaws. On the other hand, the occlusal position in patients with deformed condyles still remains to be clarified. In this review, the effectiveness and limits of centric relation in these patients are discussed. In addition, the muscle induced occlusal positions, such as the muscular position and the terminal positions of habitual closing movements, are suggested as a substitution for centric relation. Finally, the importance of a stable intercuspal position, where the habitual closing movements terminate without any premature tooth contact, is emphasized.

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The Relationship Between Retruded Contact Position and Intercuspal Position in Patients with TMJ Osteoarthritis

Cited by 6 publications

References 13 publications

Prevention of Injury-Induced Osteoarthritis in Rodent Temporomandibular Joint by Targeting Chondrocyte CaSR

Prevention of Injury-Induced Osteoarthritis in Rodent Temporomandibular Joint by Targeting Chondrocyte CaSR

Do computed tomography and magnetic resonance imaging add to temporomandibular joint disorder treatment? A systematic review of diagnostic efficacy

A controversy with respect to occlusion

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