The relationship between prenatal psychological stress and placental abruption in Japan, The Japan Environment and Children’s Study (JECS)

Abstract

Background Prenatal psychological stress may increase the risk of placental abruption (PA). This study aimed to clarify the effects of psychological distress during pregnancy and exposure to stressful life events in the year before or during pregnancy on the occurrence of PA in Japanese women. Methods Using a nationwide prospective birth cohort study, we obtained data from 103,099 women between January 2011 and March 2014. Information on exposure to 14 stressful life events and psychological distress (Kessler 6 scale) was collected using a self-administered questionnaire during pregnancy. Clinical diagnoses of PA were obtained from medical records. A total of 80,799 women with singleton births were analyzed using logistic regression models that adjusted for possible confounders. Results PA was diagnosed in 335 (0.4%) women. There was no significant difference in the Kessler 6 score during pregnancy between the PA group and non-PA group. Exposure to the death of a child in the year before or during pregnancy was significantly associated with PA in multigravid women (adjusted odds ratio [aOR] 3.57; 95% confidence interval [CI] 1.50–8.34). A spouse’s loss of employment was significantly associated with PA in parous women (aOR 3.25; 95% CI 1.40–7.56). Conclusions This study identified the possible effects of exposure to the death of a child on PA occurrence that adjusted for important confounding factors.

The quantity and quality of scientific evidence about the health of working women in occupational health of Japan: A scoping review

“…58 There was only one interventional study to assess breast self-care programs for early cancer detection, but the intervention was based on pre-and post-test without control. 59 3.10 | Infertility, pregnancy, and childbirth There were only 11 English-language articles [60][61][62][63][64][65][66][67][68][69][70] that investigated pregnant women with alcohol consumption, 63,68 smoking, 66 psychological stress, 62 depression, 61,65 and positive emotion 69 during pregnancy, and long working hours and shift work on pregnancy outcome, 64,67 trends in fertility by income and education, 60 and a desire to have an additional child of dual-earner couples. 70 However, there were 94 Japanese-language studies that investigated perinatal women related to balance with work (n = 17), breastfeeding (n = 10), infertility (n = 11), mental health (n = 13), pregnancy outcome (n = 3), and quality of life of pregnant women (n = 3); safety, work regulation, and perinatal leave (n = 17); statistics of single and birthrate with working styles (n = 2); and work, nutrition, and lifestyle (n = 18).…”

Stress of Prematurity in the Experience of the COVID-19 Pandemic—Current State of Knowledge

“…There is also an increase in the release of the pro-inflammatory cytokines IL-1β, IL-6 and tumor necrosis factor α (TNF-α) suppressing the response of the maternal immune system, which may increase the risk of preterm labor [ 38 , 41 ]. Another mechanism responsible for this phenomenon is also the constriction of placental blood vessels under the influence of cortisol, increasing blood pressure and the formation of pro-inflammatory changes responsible for the ischemia of the uterine muscle and, consequently, the occurrence of preterm labor, as well as intrauterine fetal growth restriction [ 42 ]. Overactivity of the HPA axis is also responsible for the occurrence of depression in pregnant women and an increase in the level of already experienced stress [ 39 ].…”

MIESRA mHealth: Marital satisfaction during pregnancy

“…This condition can have an impact on miscarriage, or the baby is born with stunting and both mental and physical disabilities [10,11]. Other conditions are such as abortion, premature delivery, pre-eclampsia, placental abruption, and lack of concern for the foetus [12][13][14][15]. Not only does it have an impact on the growth and development of the foetus, but also this condition has an impact on the condition of marital satisfaction, which leads to miscommunication and disharmony [16,17].…”