The Relationship Between Premature Ventricular Complexes Burden and Cardiac-Electrophysiologic Balance Index After Premature Ventricular Complex Catheter Ablation

Abstract

Backround Sudden cardiac death due to ventricular tachyarrhythmias is a global concern. Electrocardiogram (ECG) parameters can predict ventricular arrhythmias. Premature ventricular complexes (PVCs) are common arrhythmias, potentially triggering life-threatening events. The index of cardiac electrophysiological balance (iCEB) is hypothesized to predict arrhythmias. This study aimed to correlate iCEB with PVC burden post-catheter ablation. Methods Ninety-eight patients without structural heart disease underwent PVC catheter ablation. Successful ablation was defined as PVC elimination without recurrence. iCEB was calculated from resting ECG. Patients were categorized based on PVC burden. Statistical analysis was performed using SPSS. Results No significant differences in cardiovascular risk factors were found among groups. Lower iCEBc was associated with higher PVC burden. An iCEBc value of 4.87 had 72% specificity and 65.2% sensitivity for predicting PVC burden. Conclusion The study suggests that iCEBc is a promising predictor for post-ablation PVC burden, indicating its potential clinical utility. Further research validating these findings and elucidating underlying mechanisms is needed to enhance risk stratification and optimize patient management. Integrating iCEBc assessment into routine practice may aid in identifying high-risk patients and implementing targeted interventions. iCEBc is a non-invasive marker for predicting PVC burden following PVC catheter ablation in patients with structurally normal hearts.